Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

S Di Bella, G Sanson, J Monticelli… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections.
This bacterium is constantly evolving and poses complex challenges for clinicians, often …

Checkpoint inhibitor-induced colitis: From pathogenesis to management

M Terrin, G Migliorisi, A Dal Buono… - International Journal of …, 2023 - mdpi.com
The advent of immunotherapy, specifically of immune checkpoint inhibitors (ICIs), for the
treatment of solid tumors has deeply transformed therapeutic algorithms in medical …

Crohn's disease: basic characteristics of the disease, diagnostic methods, the role of biomarkers, and analysis of metalloproteinases: A review

G Pasternak, G Chrzanowski, D Aebisher, A Myśliwiec… - Life, 2023 - mdpi.com
Crohn's disease is a chronic inflammatory bowel disease that affects the ileum and/or large
intestine. At the same time, it can also affect any other part of the human body, ie, from the …

Gut virome in inflammatory bowel disease and beyond

HM Tun, Y Peng, L Massimino, ZY Sin, TL Parigi… - Gut, 2024 - gut.bmj.com
Objective The gut virome is a dense community of viruses inhabiting the gastrointestinal tract
and an integral part of the microbiota. The virome coexists with the other components of the …

[HTML][HTML] Very Early Onset-IBD: evidence for the need of a multidisciplinary approach

P Parente, M Pastore, F Grillo, M Fassan… - Pathologica, 2022 - ncbi.nlm.nih.gov
Very early onset inflammatory bowel disease (VEO-IBD) represents approximately 25% of
cases of IBD-like colitis occurring during childhood and, by definition, it is characterized by …

Ileal pouch–anal anastomosis and pouchitis: the role of the microbiota in the pathogenesis and therapy

R Gabbiadini, A Dal Buono, C Correale, A Spinelli… - Nutrients, 2022 - mdpi.com
Inflammatory bowel diseases, Crohn's disease and ulcerative colitis, are life-long disorders
characterized by the chronic relapsing inflammation of the gastrointestinal tract with the …

Inflammatory Bowel Diseases: Does One Histological Score Fit All?

V Villanacci, R Del Sordo, TL Parigi, G Leoncini… - Diagnostics, 2023 - mdpi.com
Mucosal healing (MH) is the main treatment target in ulcerative colitis (UC) and Crohn's
disease, and it is defined by the combination of complete endoscopic and histologic …

[HTML][HTML] Histopathology of Non-IBD Colitis. A practical approach from the Italian Group for the study of the gastrointestinal tract (GIPAD)

V Villanacci, L Reggiani-Bonetti, G Leoncini… - Pathologica, 2021 - ncbi.nlm.nih.gov
Non-IBD colitides (NIBDC) are intestinal diseases clinically and endoscopically overlapping
with Inflammatory Bowel Diseases (IBD), sometimes with a similar histological picture …

Animal models of inflammatory bowel disease: category and evaluation indexes

C Wen, D Chen, R Zhong, X Peng - Gastroenterology Report, 2024 - academic.oup.com
Inflammatory bowel disease (IBD) research often relies on animal models to study the
etiology, pathophysiology, and management of IBD. Among these models, rats and mice are …

Long-term behavior and functional outcomes of ileal-pouch anal anastomosis in inflammatory bowel disease with changing phenotype

A Macleod, MA Parks, CN Cook, RE Petras… - Surgery, 2024 - Elsevier
Background Ileal-pouch-anal anastomosis is the operation of choice after proctocolectomy
for ulcerative colitis; some patients will develop Crohn's disease. We aim to determine long …