Hodgkin lymphoma (HL) is a unique hematopoietic neoplasm characterized by cancerous
Reed‐Sternberg cells in an inflammatory background. Patients are commonly diagnosed …

Programmed cell death protein 1 (PD-1) blockade targeting the PD-1 immune checkpoint
has demonstrated unprecedented clinical efficacy in the treatment of advanced cancers …

Background Phenotypic characterization of immune cells in the bone marrow (BM) of
patients with acute myeloid leukemia (AML) is lacking. Methods T‐cell infiltration was …

Given the limited treatment options for relapsed lymphoma post–allogeneic hematopoietic
cell transplantation (post–allo-HCT) and the success of programmed death 1 (PD-1) …

Extranodal natural killer/T-cell lymphoma, nasal type (ENKL) is a subtype of mature T-and
natural killer cell lymphomas characterized by its association with Epstein-Barr virus and …

Richter transformation (RT) is a rare complication of chronic lymphocytic leukemia (CLL) that
has dismal outcomes. Upregulation of PD-1/PD-L1 drives immunological evasion in patients …

Investigators are using checkpoint inhibitors (CPIs) to treat aggressive hematologic
malignancies in patients undergoing allogeneic hematopoietic stem cell transplantation (allo …

Relapse of the original disease is a major cause of death after allogeneic hematopoietic cell
transplantation for acute leukemias. There is growing evidence that relapses may be …

With the advent of immunotherapeutic agents, durable and dramatic responses have been
observed in several hard-to-treat malignancies, outlining a roadmap to conquering cancer …

The development of immune checkpoint inhibitors represents a major breakthrough in the
field of cancer therapeutics. Pursuant to their success in melanoma and numerous solid …