Mesenchymal stromal cells (MSCs) are characterized by an extraordinary capacity to
modulate the phenotype and functional properties of various immune cells that play an …

In the absence of timely and proper treatments, injuries to articular cartilage (AC) can lead to
cartilage degeneration and ultimately result in osteoarthritis. Regenerative medicine and …

Background: Mesenchymal stem cell (MSC)-derived exosomes are well recognized
immunomodulating agents for cardiac repair, while the detailed mechanisms remain elusive …

Mesenchymal stem cells (mesenchymal stromal cells, MSC) are multipotent stem cells that
can differentiate into cells of at least three mesodermal lineages, namely adipocytes …

Inflammatory bowel diseases (IBDs) represent a group of chronic inflammatory disorders of
the gastrointestinal (GI) tract including ulcerative colitis (UC), Crohn's disease (CD), and …

Abstract Background Mesenchymal stromal cells (MSCs) show great potential for
immunomodulatory and anti-inflammatory treatments. Clinical trials have been performed for …

Stem cells represent an attractive resource for cardiac regeneration. However, the survival
and function of transplanted stem cells is poor and remains a major challenge for the …

Abstract Cytokine (s) pre-activation/licensing is an effective way to enhance the
immunomodulatory potency of mesenchymal stromal cells (MSCs). Currently, IFN-γ …

Simple Summary Osteoarthritis (OA) is a common condition affecting horses and humans.
The role of the innate immune system in the pathogenesis and progression of OA has been …

Bone-marrow-derived mesenchymal stem cells and endothelial progenitor cells have some
interesting biological properties that make them unique for cell therapy of degenerative and …