In the past decade, novel lamellar keratoplasty techniques such as Deep Anterior Lamellar
Keratoplasty (DALK) for anterior keratoplasty and Descemet stripping automated endothelial …

Most higher animals require sight for survival, yet even minor distortions of the visual axis
can cause blindness. For this reason, intraocular inflammation is incompatible with good …

Recognition of donor antigens by recipient T cells in secondary lymphoid organs initiates the
adaptive inflammatory immune response leading to the rejection of allogeneic transplants …

Corneal transplantation is the most successful solid organ transplantation performed in
humans. The extraordinary success of orthotopic corneal allografts, in both humans and …

The tear film, lacrimal glands, corneal and conjunctival epithelia and Meibomian glands
work together as a lacrimal functional unit (LFU) to preserve the integrity and function of the …

Disruption of the precise balance of positive and negative molecular regulators of blood and
lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors …

The internal surfaces of the human body are covered by distinct types of epithelial cells and
mucus-secreting cells. The mucosal surfaces serve many vital functions, such as respiration …

Corneal antigen-presenting cells (APC), including dendritic cells (DC), were thought to
reside exclusively in the peripheral cornea. Here, we present recent data from our group …

purpose. Dendritic cells (DCs) comprise a system of highly efficient antigen-presenting cells
(APCs) that initiate immune responses. The purpose of this study was to examine the normal …

Allografts are afforded a level of protection from rejection within immune-privileged tissues.
Immune-privileged tissues involve mechanisms that suppress inflammation and promote …