The design of artificial enzymes has emerged as a promising tool for the generation of
potent biocatalysts able to promote new-to-nature reactions with improved catalytic …

As a means to develop new tools to manipulate biological systems, transition metals have
been looked upon as an area of high potential due to the bioorthogonality of new‐to‐nature …

Artificial metalloenzymes have emerged as biohybrid catalysts that allow to combine the
reactivity of a metal catalyst with the flexibility of protein scaffolds. This work reports the …

The effect of halide substitution in Grubbs-Hoveyda II catalysts (GHII catalysts) embedded in
the engineered β-barrel protein nitrobindin (NB4exp) on metathesis activity in aqueous …

The potential of artificial metalloenzymes has led to an increase in interest for the design of
novel metal-binding sites in proteins. Metal-chelating unnatural amino acids offer an …

Eine weitere Schwierigkeit für die gelenkte Evolution ist, den besten Startpunkt zu finden–
welcher bietet das größte Optimierungspotenzial? Da die aktiven Zentren natürlicher …

Evolution im Reagenzglas Page 1 66 Wissenschaft + Forschung Nachrichten aus der
Chemie| 70 | September 2022 | www.gdch.de/nachrichten Längst haben Synthesechemi …