Single-cell transcriptomics reveals that glial cells integrate homeostatic and circadian processes to drive sleep–wake cycles

J Dopp, A Ortega, K Davie, S Poovathingal… - Nature …, 2024 - nature.com
The sleep–wake cycle is determined by circadian and sleep homeostatic processes.
However, the molecular impact of these processes and their interaction in different brain cell …

Regulatory mechanism of cold-inducible diapause in Caenorhabditis elegans

M Horikawa, M Fukuyama, A Antebi… - Nature …, 2024 - nature.com
Temperature is a critical environmental cue that controls the development and lifespan of
many animal species; however, mechanisms underlying low-temperature adaptation are …

[PDF][PDF] Insect PRXamides: Evolutionary divergence, novelty, and loss in a conserved neuropeptide system

SM Farris - Journal of Insect Science, 2023 - academic.oup.com
The PRXamide neuropeptides have been described in both protostome and deuterostome
species, including all major groups of the Panarthropoda. Best studied are the insect …

Age‐regulated cycling metabolites are relevant for behavior

JE Schwarz, A Sengupta, C Guevara, AF Barber… - Aging cell, 2024 - Wiley Online Library
Circadian cycles of sleep: wake and gene expression change with age in all organisms
examined. Metabolism is also under robust circadian regulation, but little is known about …

The NFκB Dif is required for behavioral and molecular correlates of sleep homeostasis in Drosophila

MK O'Hara, C Saul, A Handa, B Cho, X Zheng… - Sleep, 2024 - academic.oup.com
The nuclear factor binding the κ light chain in B-cells (NFκB) is involved in a wide range of
cellular processes including development, growth, innate immunity, and sleep. However …

[HTML][HTML] Neuropeptide-dependent spike time precision and plasticity in circadian output neurons

B Chong, V Kumar, DL Nguyen, MA Hopkins… - …, 2024 - pmc.ncbi.nlm.nih.gov
Circadian rhythms influence various physiological and behavioral processes such as sleep-
wake cycles, hormone secretion, and metabolism. In Drosophila, an important set of …

ninna nanna links circadian and homeostatic sleep drive in Drosophila

A Petzold, GF Gilestro - bioRxiv, 2024 - biorxiv.org
Sleep is under control of two processes, circadian and homeostatic regulation, but little is
known about how these two processes integrate. Here, we identify a Drosophila gene, ninna …

Neuropeptides from a praying mantis: What the loss of pyrokinins and tryptopyrokinins suggests about the endocrine functions of these peptides

JA Veenstra - bioRxiv, 2024 - biorxiv.org
Background. Neuropeptides play important roles in insects, but in many cases their functions
remain obscure. Comparative neuropeptidome analyses may provide clues to what these …

[HTML][HTML] Dataset for Doctoral Thesis' Physiology of rest/activity cycles in Drosophila melanogaster'

J Anns, J Stewart, L Bullivant, L Jackson - 2024 - eprints.soton.ac.uk
DAM_Minute,DAM_Sleep,BeamBreaks,Total_Frames,SSB,SSL,SS,SA,LO,Fly,ZT 1.0,0.0,5.0,2701,0.0,0.0,5.072195483154387,7.034431691965938,87.89337282487968,0,11.016665
2.0,0.0,5.0,2700,0.0,0.0,2.851851851851852,8.444444444444445,88.70370370370371,0,11.03333 …