Dasatinib-loaded topical nano-emulgel for rheumatoid arthritis: Formulation design and optimization by QbD, in vitro, ex vivo, and In vivo evaluation

MR Donthi, RN Saha, G Singhvi, SK Dubey - Pharmaceutics, 2023 - mdpi.com
The current study aimed to develop a topical emulgel of dasatinib (DTB) for rheumatoid
arthritis (RA) treatment to reduce systemic side effects. The quality by design (QbD) …

Development and validation of a stability‐indicating reversed‐phase–high‐performance liquid chromatography method for quantification of 2‐[1‐hexyloxyethyl]‐2 …

R Pradhan, SK Dubey, A Puri… - Separation Science …, 2023 - Wiley Online Library
[1‐hexyloxyethyl]‐2‐devinyl pyropheophorbide‐a is a second‐generation, lipophilic, chlorin‐
based photosensitizer currently used for various types of solid cancer including breast …

[HTML][HTML] Overview of sources, fate, and Impact of Endocrine Disrupting Compounds in environment and assessment of their Regulatory Policies across different …

A Singh, G Singh, P Singh, VK Mishra - Total Environment Research …, 2023 - Elsevier
Under the present research we have reviewed the sources, fate of Endocrine Disrupting
Compounds (EDCs) and its impact on the health of both human and the environment …

Simultaneous estimation of parabens and bisphenol a in ready-to-eat foodstuffs by using QbD-driven high-pressure liquid chromatography method

R Pradhan, S Hejmady, R Taliyan… - International Journal …, 2022 - Taylor & Francis
Endocrine-disrupting chemicals (EDC) are harmful xenobiotics show casingv aried
unwanted effects altering the endocrine system and its functions. Exposure of EDCs to …

Analytical quality by design for high-performance thin-layer chromatography method development

S Hejmady, D Choudhury, R Pradhan, G Singhvi… - Handbook of analytical …, 2021 - Elsevier
Quality by design (QbD) is a logical and scientific strategy employed for the development of
a pharmaceutical product. It is initiated with predefined objectives and deals with the …

Implementation of Quality by Design Approach for Optimization of RP-HPLC Method for Quantification of Abiraterone Acetate in Solid Dispersion in Forced …

M Choudhari, MR Donthi, S Damle… - Current …, 2022 - ingentaconnect.com
Background: Abiraterone acetate is a derivative of steroidal progesterone, used as a firstline
therapy for metastatic castration of prostate cancer. Objectives: The present study …

Simultaneous estimation of methyl paraben, propyl paraben, and Bisphenol A in the plasma of Indian pregnant women using liquid chromatography–tandem mass …

R Pradhan, D Mishra, SK Dubey… - Separation …, 2023 - Wiley Online Library
A selective, rapid, and novel bioanalytical method was developed for the simultaneous
determination of methyl paraben, propyl paraben, and Bisphenol A in human plasma with a …

Presencia de contaminantes orgánicos prioritarios y emergentes en material particulado atmosfético (PM10 y PM2. 5) de un entorno urbano de A Coruña

L Mosteiro Díaz - 2023 - ruc.udc.es
En el presente trabajo se estudia la presencia de 50 compuestos orgánicos emergentes y
prioritarios en muestras de material particulado atmosférico (fracciones PM2. 5 y PM10 …

Bioanalytical methodologies for clinical investigation of endocrine-disrupting chemicals: a comprehensive update

R Pradhan, S Hejmady, R Taliyan, G Singhvi… - Bioanalysis, 2021 - Taylor & Francis
Endocrine-disrupting chemicals (EDCs) are xenobiotics that disrupt the endocrine system in
humans at ecologically significant concentrations. Various substances are exposed to …

Analytical quality by design for gas chromatographic method development

R Pradhan, S Hejmady, A Alexander, G Singhvi… - Handbook of Analytical …, 2021 - Elsevier
Quality by design (QbD) is a scientific approach in pharmaceutical product development
beginning with predefined goals and utilizes scientific knowledge and risk management …