Multiscale Modeling of Respiratory Transport Phenomena and Intersubject Variability
SC Kassinos, J Sznitman - Annual Review of Fluid Mechanics, 2024 - annualreviews.org
Our understanding of respiratory flow phenomena has been consolidated over decades with
the exploration of in vitro and in silico canonical models that underscore the multiscale fluid …
the exploration of in vitro and in silico canonical models that underscore the multiscale fluid …
Mucus, airway and plume temperature effects on pMDI-drug delivery in a mouth-throat airway: Experimental and numerical studies
M Jahed, J Kozinski, L Pakzad - Journal of Aerosol Science, 2024 - Elsevier
Effective pulmonary drug delivery through pressurized-metered dose inhalers (pMDIs)
depends on accurately targeting pharmaceutical aerosols to specific lung areas. Achieving …
depends on accurately targeting pharmaceutical aerosols to specific lung areas. Achieving …
Effect of transient breathing cycle on the deposition of micro and nanoparticles on respiratory walls
Background and objective From various perspectives (eg inhalation exposure and drug
delivery), it is important to provide insights into the behavior of inhaled particles in the …
delivery), it is important to provide insights into the behavior of inhaled particles in the …
[HTML][HTML] Effects of the deformation and size of the upper airway on the deposition of aerosols
Aerosol drug delivery in the human airway is significantly affected by the morphology and
size of the airway. This work developed a CFD-DEM model to simulate and analyze air flow …
size of the airway. This work developed a CFD-DEM model to simulate and analyze air flow …
Numerical simulation of virus-laden aerosol transmission in real human respiratory airways
In this study, the transport of virus-laden aerosols in real human airways is investigated
through numerical simulations. Three different breathing modes (nasal, oral, and nasal–oral) …
through numerical simulations. Three different breathing modes (nasal, oral, and nasal–oral) …
Assessing airflow unsteadiness in the human respiratory tract under different expiration conditions
To enhance the understanding of airflow characteristics in the human respiratory system, the
expiratory airflow in a human respiratory tract model was simulated using large eddy …
expiratory airflow in a human respiratory tract model was simulated using large eddy …
Engineering nanoliposomal tiotropium bromide embedded in a lactose-arginine carrier forming Trojan-particle dry powders for efficient pulmonary drug delivery: A …
Nanocarrier-based dry powders for lung disease treatment are crucial, with in vitro and in
silico research being pivotal to their success. This study introduces a method for creating …
silico research being pivotal to their success. This study introduces a method for creating …
Optimal Treatment of Tumor in Upper Human Respiratory Tract Using Microaerosols
Lung cancer is a frequently diagnosed respiratory disease caused by particulate matter in
the environment, especially among older individuals. For its effective treatment, a promising …
the environment, especially among older individuals. For its effective treatment, a promising …
Coupled Discrete Phase and Eulerian Wall Film Models for Drug Deposition Efficacy Analysis in Human Respiratory Airways
The current study explores the effectiveness of drug particle deposition into human
respiratory airways to cure various pulmonary-bound ailments. It has been assumed that …
respiratory airways to cure various pulmonary-bound ailments. It has been assumed that …
The impact of asymmetric branching on particle deposition in conducting airways
S Ghorui, D Kundu, A Chakravarty… - International Journal of …, 2024 - Elsevier
Inhalation exposes individuals to a diverse range of airborne particles carrying potential
health risks. Airflow and particle transport behavior is highly sensitive to airway geometry …
health risks. Airflow and particle transport behavior is highly sensitive to airway geometry …