Mast cells are tissue-inhabiting cells that play an important role in inflammatory diseases of
the airway tract. Mast cells arise in the bone marrow as progenitor cells and complete their …

Hydroxyeicosatetraenoic acids (HETEs) are metabolites of arachidonate acid (AA) oxidized
by lipoxygenases or cytochrome P450 enzymes (CYP450). Since lipoxygenases and …

Background: Eosinophils have numerous roles in type 2 inflammation depending on their
activation states in the blood and airway or after encounter with inflammatory mediators …

Enzymatically oxygenated phospholipids (eoxPL) from lipoxygenases (LOX) or
cyclooxygenase (COX) are prothrombotic. Their generation in arterial disease, and their …

Age-related macular degeneration (AMD) is a degenerative disease that severely impairs
vision, often accompanied by oxidative stress damage, cellular apoptosis, and inflammatory …

Background Noninvasive biomarkers for diagnosing and monitoring eosinophilic
esophagitis (EoE) are currently lacking. This study evaluates 20 biomarkers in serum and …

Background: Eosinophils have numerous roles in type 2 inflammation depending on their
activation states in the blood and airway or after encounter with inflammatory mediators …

Exercise-induced bronchoconstriction (EIB) is thought to be triggered by increased
osmolarity at the airway epithelium. The aim of this study was to define the contractile …

Oxylipin signaling has been suggested as a potential mechanism for the inter-partner
recognition and homeostasis regulation of cnidarian-dinoflagellate symbiosis, which …

Enzymatically oxygenated phospholipids (eoxPL) formed by lipoxygenases (LOX) and
cyclooxygenase (COX) in platelets and leukocytes are pro-coagulant in multiple model …