[HTML][HTML] Long non-coding RNA in the pathogenesis of cancers

Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

HOTAIR LncRNA: a novel oncogenic propellant in human cancer

T Rajagopal, S Talluri, RL Akshaya, NR Dunna - Clinica chimica acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …

[HTML][HTML] Functional interaction among lncRNA HOTAIR and microRNAs in cancer and other human diseases

M Cantile, M Di Bonito, M Tracey De Bellis, G Botti - Cancers, 2021 - mdpi.com
Simple Summary This review aimed to describe the contribution of functional interaction
between the lncRNA HOTAIR and microRNAs in human diseases, including cancer …

[HTML][HTML] LncRNA HOTAIR is a prognostic biomarker for the proliferation and chemoresistance of colorectal cancer via MiR-203a-3p-mediated Wnt/ss-catenin signaling …

Z Xiao, Z Qu, Z Chen, Z Fang, K Zhou… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: HOX transcript antisense RNA (HOTAIR) plays a vital role in
carcinogenesis. However, its functional and regulatory roles remain unclear. In this study …

The role of long non-coding RNAs in breast cancer

M Soudyab, M Iranpour… - Archives of Iranian …, 2016 - journalaim.com
Long non-coding RNA (lncRNA) genes are an important population of non-coding RNAs
with defined key roles in normal development as well as tumorigenesis process. Evidences …

[HTML][HTML] Long Non-Coding RNA HOTAIR in Breast Cancer Therapy

M Cantile, M Di Bonito, M Cerrone, F Collina… - Cancers, 2020 - mdpi.com
Breast cancer (BC) is the most common cancer type among women, and morbidity and
mortality rates are still very high. Despite new innovative therapeutic approaches for all BC …

[HTML][HTML] Long non-coding RNAs as prognostic markers in human breast cancer

H Liu, J Li, P Koirala, X Ding, B Chen, Y Wang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) have been recently shown to play an important role in
gene regulation and normal cellular functions, and disease processes. However, despite the …

[HTML][HTML] Knockdown of lncRNA‑HOTAIR downregulates the drug‑resistance of breast cancer cells to doxorubicin via the PI3K/AKT/mTOR signaling pathway

Z Li, J Qian, J Li, C Zhu - Experimental and therapeutic …, 2019 - spandidos-publications.com
The resistance to chemotherapeutic drugs is a critical feature of breast cancer recurrence
and metastasis. Long non‑coding RNAs (LncRNAs) serve key roles in tumor drug …

[HTML][HTML] The impact of lncRNA dysregulation on clinicopathology and survival of breast cancer: a systematic review and meta-analysis

T Tian, M Wang, S Lin, Y Guo, Z Dai, K Liu… - … Therapy-Nucleic Acids, 2018 - cell.com
Dysregulation of multiple long non-coding RNAs (lncRNAs) was reported to play major roles
in breast cancer (BC). Here we aimed to collect most of the relevant literature to assess the …

Long noncoding RNAs in aging and age-related diseases

S Kour, PC Rath - Ageing research reviews, 2016 - Elsevier
Aging is the universal, intrinsic, genetically-controlled, evolutionarily-conserved and time-
dependent intricate biological process characterised by the cumulative decline in the …