Motor symptoms in Parkinson's disease: A unified framework

AA Moustafa, S Chakravarthy, JR Phillips… - Neuroscience & …, 2016 - Elsevier
Parkinson's disease (PD) is characterized by a range of motor symptoms. Besides the
cardinal symptoms (akinesia and bradykinesia, tremor and rigidity), PD patients show …

Cognitive contributions to gait and falls: evidence and implications

M Amboni, P Barone, JM Hausdorff - Movement disorders, 2013 - Wiley Online Library
Dementia and gait impairments often coexist in older adults and patients with
neurodegenerative disease. Both conditions represent independent risk factors for falls. The …

Gait and cognition: Mapping the global and discrete relationships in ageing and neurodegenerative disease

R Morris, S Lord, J Bunce, D Burn… - … & Biobehavioral Reviews, 2016 - Elsevier
Recent research highlights the association of gait and cognition in older adults but a
stronger understanding is needed to discern coincident pathophysiology, patterns of …

Magnetic resonance imaging for the diagnosis of Parkinson's disease

B Heim, F Krismer, R De Marzi, K Seppi - Journal of neural transmission, 2017 - Springer
The differential diagnosis of parkinsonian syndromes is considered one of the most
challenging in neurology and error rates in the clinical diagnosis can be high even at …

Neuroimaging advances in Parkinson's disease and atypical Parkinsonian syndromes

U Saeed, AE Lang, M Masellis - Frontiers in neurology, 2020 - frontiersin.org
Parkinson's disease (PD) and atypical Parkinsonian syndromes are progressive
heterogeneous neurodegenerative diseases that share clinical characteristic of …

Neuroimaging in Parkinson disease: from research setting to clinical practice

M Politis - Nature Reviews Neurology, 2014 - nature.com
Over the past three decades, neuroimaging studies—including structural, functional and
molecular modalities—have provided invaluable insights into the mechanisms underlying …

Characterizing freezing of gait in Parkinson's disease: models of an episodic phenomenon

A Nieuwboer, N Giladi - Movement Disorders, 2013 - Wiley Online Library
Freezing of gait (FOG) is a very disabling and common gait disorder in Parkinson's disease
(PD). The first aim of this article was to provide a methodological and critical review of the …

Asymmetric pedunculopontine network connectivity in parkinsonian patients with freezing of gait

BW Fling, RG Cohen, M Mancini, JG Nutt, DA Fair… - Brain, 2013 - academic.oup.com
Freezing of gait is one of the most debilitating symptoms in Parkinson's disease as it causes
falls and reduces mobility and quality of life. The pedunculopontine nucleus is one of the …

Gray matter, white matter and cerebrospinal fluid abnormalities in Parkinson's disease: A voxel-based morphometry study

CO Nyatega, L Qiang, MJ Adamu… - Frontiers in Psychiatry, 2022 - frontiersin.org
Background Parkinson's disease (PD) is a chronic neurodegenerative disorder
characterized by bradykinesia, tremor, and rigidity among other symptoms. With a 70 …

Exploring the cortical and subcortical functional magnetic resonance imaging changes associated with freezing in Parkinson's disease

JM Shine, E Matar, PB Ward, SJ Bolitho, M Gilat… - Brain, 2013 - academic.oup.com
Freezing of gait is a devastating symptom of advanced Parkinson's disease yet the neural
correlates of this phenomenon remain poorly understood. In this study, severity of freezing of …