Early drug development and evaluation of putative antitubercular compounds in the-omics era
A Minias, L Żukowska, E Lechowicz, F Gąsior… - Frontiers in …, 2021 - frontiersin.org
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium
tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of …
tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of …
Comparative Genome and Network Centrality Analysis to Identify Drug Targets of Mycobacterium tuberculosis H37Rv
Potential drug targets of Mycobacterium tuberculosis H37Rv were identified through
systematically integrated comparative genome and network centrality analysis. The …
systematically integrated comparative genome and network centrality analysis. The …
Identification and architecture of a putative secretion tube across mycobacterial outer envelope
Tuberculosis-causing mycobacteria have thick cell-wall and capsule layers that are formed
from complex structures. Protein secretion across these barriers depends on a specialized …
from complex structures. Protein secretion across these barriers depends on a specialized …
An in silico approach to identify potential inhibitors against multiple drug targets of Mycobacterium tuberculosis
S Kumar, P Sahu, L Jena - The International Journal of …, 2019 - journals.lww.com
Background: The increasing incidence of multidrug-resistant cases of tuberculosis (TB) and
difficulty in treating these cases requires an urgent need to find an effective anti-TB drug …
difficulty in treating these cases requires an urgent need to find an effective anti-TB drug …
Integrating Multifaceted Information to Predict Mycobacterium tuberculosis-Human Protein-Protein Interactions
J Sun, LL Yang, X Chen, DX Kong… - Journal of proteome …, 2018 - ACS Publications
Tuberculosis (TB) is one of the biggest infectious disease killers caused by Mycobacterium
tuberculosis (MTB). Studying the protein-protein interactions (PPIs) between MTB and …
tuberculosis (MTB). Studying the protein-protein interactions (PPIs) between MTB and …
Comparative analysis of Rosetta stone events in Klebsiella pneumoniae and Streptococcus pneumoniae for drug target identification
P Ramesh, JH Nagendrappa… - Beni-Suef University …, 2021 - Springer
Background Drug target identification is a fast-growing field of research in many human
diseases. Many strategies have been devised in the post-genomic era to identify new drug …
diseases. Many strategies have been devised in the post-genomic era to identify new drug …
Maximum flow approach to prioritize potential drug targets of Mycobacterium tuberculosis H37Rv from protein-protein interaction network
Background In spite of the implementations of several strategies, tuberculosis (TB) is
overwhelmingly a serious global public health problem causing millions of infections and …
overwhelmingly a serious global public health problem causing millions of infections and …
Structural analysis of protein translocase subunit SecY from Mycobacterium tuberculosis H37Rv: a potential target for anti-tuberculosis drug discovery
Identification of noble drug targets is a very important step in the development of anti-
mycobacterial drugs to counter the problem of drug resistance. The availability of structural …
mycobacterial drugs to counter the problem of drug resistance. The availability of structural …
Genome scale identification, structural analysis, and classification of periplasmic binding proteins from Mycobacterium tuberculosis
Periplasmic-binding proteins occupy the periplasmic space of bacteria and are involved in
binding and transport of various ions, siderophores, and other diverse types of solutes …
binding and transport of various ions, siderophores, and other diverse types of solutes …
[PDF][PDF] Topological Characterization of Protein-Protein Interaction via Implementing Large Scale Interaction Networks in Mycobacterium Tuberculosis H37Rv
This research manuscript essentially emphasizes the retrieval of Mycobacterium
Tuberculosis H37Rv SuperTarget proteins to provide STRING Database with network …
Tuberculosis H37Rv SuperTarget proteins to provide STRING Database with network …