The interplay between uremic toxins and albumin, membrane transporters and drug interaction
RS Cunha, CAB Azevedo, CA Falconi, FF Ruiz… - Toxins, 2022 - mdpi.com
Uremic toxins are a heterogeneous group of molecules that accumulate in the body due to
the progression of chronic kidney disease (CKD). These toxins are associated with kidney …
the progression of chronic kidney disease (CKD). These toxins are associated with kidney …
Regulation of renal organic cation transporters
M Pernecker, G Ciarimboli - FEBS letters, 2024 - Wiley Online Library
Transporters for organic cations (OCs) facilitate exchange of positively charged molecules
through the plasma membrane. Substrates for these transporters encompass …
through the plasma membrane. Substrates for these transporters encompass …
[HTML][HTML] Effect of 7-ketocholesterol incorporation on substrate binding affinity and turnover rate of the organic cation transporter 2 (OCT2)
F Xiu, L Console, C Indiveri, S Su, T Wang… - Biochemical …, 2024 - Elsevier
The organic cation transporter 2 (OCT2) is pivotal in the renal elimination of several
positively charged molecules. OCT2 mode of transport is profoundly influenced by the level …
positively charged molecules. OCT2 mode of transport is profoundly influenced by the level …
Involvement of Inflammatory Cytokines, Renal NaPi-IIa Cotransporter, and TRAIL Induced-Apoptosis in Experimental Malaria-Associated Acute Kidney Injury
GM Simião, KS Parreira, SG Klein, FB Ferreira… - Pathogens, 2024 - mdpi.com
The murine model of experimental cerebral malaria (ECM) induced by Plasmodium berghei
ANKA was used to investigate the relationship among pro-inflammatory cytokines …
ANKA was used to investigate the relationship among pro-inflammatory cytokines …
Huangqi Jiuni decoction prevents acute kidney injury induced by severe burns by inhibiting activation of the TNF/NF-κB pathway
W Hu, J Zhao, Y Hu, S Song, X Chen, Y Sun - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Huangqi Jiuni decoction (HQJND) is a
prescription for the treatment of severe burns provided based on traditional Chinese and …
prescription for the treatment of severe burns provided based on traditional Chinese and …
Development and validation of a prediction model for estimating 24-Hour Urinary Sodium Excretion using spot urine samples in adult patients
M Menacho-Roman, M Fabregate-Fuente… - Journal of Renal …, 2024 - Elsevier
The measurement of urinary sodium excretion provides valuable information about an
individual's sodium balance and can help in the management of various medical conditions …
individual's sodium balance and can help in the management of various medical conditions …
Optimizing anticancer pharmacotherapy in kidney disease: Estimation of kidney function and evaluation of heterogeneous kinase inhibitor pharmacokinetics
MA Butrovich - 2024 - d-scholarship.pitt.edu
Kidney disease is common in cancer patients, with almost 20% of all solid tumor patients
having an estimated glomerular filtration rate (GFR; eGFR)< 60 mL/min. Kidney function is …
having an estimated glomerular filtration rate (GFR; eGFR)< 60 mL/min. Kidney function is …
[PDF][PDF] MASTERARBEIT/MASTER'S THESIS
TJF Angenoorth - 2022 - phaidra.univie.ac.at
High-affinity and low-capacity transporters for norepinephrine (NET; norepinephrine
transporter; SLC6A2), dopamine (DAT; dopamine transporter; SLC6A3), and serotonin …
transporter; SLC6A2), dopamine (DAT; dopamine transporter; SLC6A3), and serotonin …