Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease with multi-organ
involvement, fibrosis and vasculopathy. Treatment in SSc, including early diffuse cutaneous …

Systemic Sclerosis (SSc) is an autoimmune disease marked by dysregulation of the immune
system, tissue fibrosis and dysfunction of the vasculature. Vascular damage, remodeling and …

Raynaud's phenomenon (RP) is common, affecting approximately 5% of the population, and
is important to the rheumatologist because it is often the presenting symptom of connective …

Raynaud's phenomenon (RP) is a common vasospastic condition which affects~ 5% of the
general population. The majority of individuals have primary RP; however, Raynaud's can …

Raynaud's phenomenon is a painful vascular condition in which abnormal vasoconstriction
of the digital arteries causes blanching of the skin. The treatment approach can vary …

Raynaud's phenomenon, which is characterized by episodic digital pallor, cyanosis and
rubor upon exposure to cold environment or to stress, is relatively common, although the …

Raynaud phenomenon (RP) presents with either primary or secondary disease, and both
have the potential to negatively impact patient quality of life. First-line management of RP …

ABSTRACT Introduction Systemic sclerosis (SSc) is a multi-dimensional connective tissue
disease of unknown etiology. Given the immense clinical complexity of SSc, the treatment of …

Systemic sclerosis (SSc) is a rare connective tissue disease characterized by skin and
visceral fibrosis, vascular hyperreactivity and obliterative vasculopathy. Some of its …

Raynaud's phenomenon and digital ulcers: advances in evaluat... : Current Opinion in
Rheumatology Raynaud's phenomenon and digital ulcers: advances in evaluation and …