Glucocorticoids exert anti-inflammatory and immunosuppressive activities by genomic and
nongenomic effects. The classic genomic effects are mediated by cytosolic glucocorticoid …

Primary Membranous Nephropathy (PMN) is the most frequent cause of nephrotic syndrome
in adults. If untreated, PMN can lead to end-stage renal disease; moreover, affected patients …

Although change in proteinuria has been proposed as a surrogate for long-term prognosis in
membranous nephropathy (MGN), variability in proteinuria levels and lag between these …

Absent a remission of proteinuria, primary membranous nephropathy (MN) can lead to
ESRD over many years. Therefore, use of an earlier end point could facilitate the conduct of …

In recent decades, several important advances have taken place in the understanding of the
pathogenesis underlying membranous nephropathy (MN) that have sparked renewed …

Introduction There is broad consensus that high-grade basal proteinuria and failure to
achieve remission of proteinuria are key determinants of adverse renal prognosis in patients …

Background Patients with primary membranous nephropathy (MN) and persistent nephrotic
syndrome have a high risk of progression to end-stage renal disease. The Ponticelli protocol …

Introduction: Therapy in patients with primary membranous nephropathy is debated. The
discovery of anti-PLA2R antibodies provides opportunities for new treatment strategies …

Idiopathic or primary membranous nephropathy (IMN) is one of the most frequent causes of
nephrotic syndrome in adults and the elderly. It is characterized by a thickening of the wall of …

Background: In the last decade, great advances have been made in the field of membranous
nephropathy (MN). The autoimmune nature of the disease has been confirmed with the …