Review of the fluoropyrimidine antidote uridine triacetate
JT Thompson, DM Wood… - British Journal of Clinical …, 2024 - Wiley Online Library
Abstract In 2015, the United States Food and Drug Administration (FDA) approved uridine
triacetate to treat overdose and severe toxicity of the fluoropyrimidine chemotherapy agents …
triacetate to treat overdose and severe toxicity of the fluoropyrimidine chemotherapy agents …
Pharmacogenetics in Oncology: A useful tool for individualizing drug therapy
R Nogueiras‐Álvarez… - British Journal of Clinical …, 2024 - Wiley Online Library
With the continuous development of genetics in healthcare, there has been a significant
contribution to the development of precision medicine, which is ultimately aimed at …
contribution to the development of precision medicine, which is ultimately aimed at …
[HTML][HTML] Angelica Sinensis polysaccharide antagonizes 5-Fluorouracil-induced spleen injury and dysfunction by suppressing oxidative stress and apoptosis
K Du, L Wang, Z Wang, H Xiao, J Hou, L Hu… - Biomedicine & …, 2023 - Elsevier
Angelica Sinensis polysaccharide (ASP), the main active component of Angelica sinensis,
possesses antioxidative and anti-apoptotic properties. In this study, we have investigated the …
possesses antioxidative and anti-apoptotic properties. In this study, we have investigated the …
Discussion on the optimization of personalized medication using information systems based on pharmacogenomics: an example using colorectal cancer
M Yuan, Y Zheng, N Bai, F Wang, H Zhang… - Frontiers in …, 2025 - frontiersin.org
Pharmacogenomics (PGx) is a powerful tool for clinical optimization of drug efficacy and
safety. However, due to many factors affecting drugs in the real world, PGx still accounts for …
safety. However, due to many factors affecting drugs in the real world, PGx still accounts for …
MTHFR 677 C>T- and 1298 A>C-related adverse effects in 5-fluorouracil-based chemotherapy in the Asian population: a systematic review and meta-analysis
Y Bai, D Jiang, Y Wen, W Wang, Z Song - Discover Medicine, 2024 - Springer
Objective This study was conducted to delineate the correlation between polymorphisms in
methylenetetrahydrofolate reductase (MTHFR) and toxicity of 5-fluorouracil (5-FU)-based …
methylenetetrahydrofolate reductase (MTHFR) and toxicity of 5-fluorouracil (5-FU)-based …