Antimicrobial peptides: Application informed by evolution
BP Lazzaro, M Zasloff, J Rolff - Science, 2020 - science.org
BACKGROUND Antimicrobial peptides (AMPs) are small proteins with potent antibacterial,
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …
antiviral, and antifungal activity. AMPs are ubiquitous among multicellular eukaryotes, with …
Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications
CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …
AntiCP 2.0: an updated model for predicting anticancer peptides
Increasing use of therapeutic peptides for treating cancer has received considerable
attention of the scientific community in the recent years. The present study describes the in …
attention of the scientific community in the recent years. The present study describes the in …
Designing of a multi-epitope vaccine against the structural proteins of marburg virus exploiting the immunoinformatics approach
Marburg virus disease (MVD) caused by the Marburg virus (MARV) generally appears with
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …
flu-like symptoms and leads to severe hemorrhagic fever. It spreads via direct contact with …
PepTherDia: database and structural composition analysis of approved peptide therapeutics and diagnostics
Highlights•PepTherDia is a database containing 105 approved peptide
pharmaceuticals.•86% of approved peptide therapeutics and diagnostics are natural or …
pharmaceuticals.•86% of approved peptide therapeutics and diagnostics are natural or …
Designing improved active peptides for therapeutic approaches against infectious diseases
Infectious diseases are one of the main causes of human morbidity and mortality. In the last
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
few decades, pathogenic microorganisms' resistance to conventional drugs has been …
Benchmarking of different molecular docking methods for protein-peptide docking
Background Molecular docking studies on protein-peptide interactions are a challenging
and time-consuming task because peptides are generally more flexible than proteins and …
and time-consuming task because peptides are generally more flexible than proteins and …
Proteome-wide screening for designing a multi-epitope vaccine against emerging pathogen Elizabethkingia anophelis using immunoinformatic approaches
Elizabethkingia anophelis is an emerging human pathogen causing neonatal meningitis,
catheter-associated infections and nosocomial outbreaks with high mortality rates. Besides …
catheter-associated infections and nosocomial outbreaks with high mortality rates. Besides …
Immunoinformatics Approach for Epitope‐Based Peptide Vaccine Design and Active Site Prediction against Polyprotein of Emerging Oropouche Virus
UK Adhikari, M Tayebi… - Journal of immunology …, 2018 - Wiley Online Library
Oropouche virus (OROV) is an emerging pathogen which causes Oropouche fever and
meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil …
meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil …
In vitro genetic code reprogramming for the expansion of usable noncanonical amino acids
T Katoh, H Suga - Annual Review of Biochemistry, 2022 - annualreviews.org
Genetic code reprogramming has enabled us to ribosomally incorporate various
nonproteinogenic amino acids (npAAs) into peptides in vitro. The repertoire of usable npAAs …
nonproteinogenic amino acids (npAAs) into peptides in vitro. The repertoire of usable npAAs …