A comprehensive review on bitter gourd (Momordica charantia L.) as a gold mine of functional bioactive components for therapeutic foods

KS Gayathry, JA John - Food Production, Processing and Nutrition, 2022 - Springer
Bitter gourd is a tropical wine grown mainly in India, China and South East Asia. The plant is
cultivated mainly for its fruit part which is edible. Bitter gourd is unaccepted widely due to its …

Plant Derived Bioactive Compounds, Their Anti-Cancer Effects and In Silico Approaches as an Alternative Target Treatment Strategy for Breast Cancer: An Updated …

V Shrihastini, P Muthuramalingam, S Adarshan… - Cancers, 2021 - mdpi.com
Simple Summary Breast cancer is one of the leading causes of death among women
worldwide. Breast cancer may be provoked due to several physical, chemical and …

Bitter Melon (Momordica Charantia), a Nutraceutical Approach for Cancer Prevention and Therapy

S Sur, RB Ray - Cancers, 2020 - mdpi.com
Cancer is the second leading cause of death worldwide. Many dietary plant products show
promising anticancer effects. Bitter melon or bitter gourd (Momordica charantia) is a nutrient …

MicroRNAs and epigenetics strategies to reverse breast cancer

MM Rahman, AC Brane, TO Tollefsbol - Cells, 2019 - mdpi.com
Breast cancer is a sporadic disease with genetic and epigenetic components. Genomic
instability in breast cancer leads to mutations, copy number variations, and genetic …

Pharmacological exploitation of the phenothiazine antipsychotics to develop novel antitumor agents–A drug repurposing strategy

CH Wu, LY Bai, MH Tsai, PC Chu, CF Chiu, MY Chen… - Scientific reports, 2016 - nature.com
Phenothiazines (PTZs) have been used for the antipsychotic drugs for centuries. However,
some of these PTZs have been reported to exhibit antitumor effects by targeting various …

Bitter gourd (Momordica charantia) possess developmental toxicity as revealed by screening the seeds and fruit extracts in zebrafish embryos

MF Khan, N Abutaha, FA Nasr, AS Alqahtani… - … and alternative medicine, 2019 - Springer
Abstract Background Bitter gourd (Momordica charantia) has attracted the focus of
researchers owing to its excellent anti-diabetic action. The beneficial effect of Momordica …

Biopolymeric nanoparticles based effective delivery of bioactive compounds toward the sustainable development of anticancerous therapeutics

N Pathak, P Singh, PK Singh, S Sharma… - Frontiers in …, 2022 - frontiersin.org
Nowadays, effective cancer therapy is a global concern, and recent advances in
nanomedicine are crucial. Cancer is one of the major fatal diseases and a leading cause of …

Efficiency of novel nanocombinations of bovine milk proteins (lactoperoxidase and lactoferrin) for combating different human cancer cell lines

MM Abu-Serie, EM El-Fakharany - Scientific reports, 2017 - nature.com
Bovine lactoperoxidase (LPO) and lactoferrin (LF) are suitable proteins to be loaded or
adsorbed to chitosan nanoparticles (NPs) for preparing stable nanoformulations with potent …

Natural terpenoids against female breast cancer: a 5-year recent research

SB Ateba, MA Mvondo, ST Ngeu… - Current medicinal …, 2018 - ingentaconnect.com
Background: The approval of Taxol® in 1993 marked the great entrance of terpenoids in the
anti-cancer area and this drug is still highly important in the treatment of refractory ovarian …

Bioactive properties and phenolic profile of Momordica charantia L. medicinal plant growing wild in Trinidad and Tobago

B Svobodova, L Barros, RC Calhelha, S Heleno… - Industrial crops and …, 2017 - Elsevier
A wild variety of bitter melon Momordica charantia L.(Cucurbitaceae) has been used in bush
medicine of Trinidad and Tobago for treatment of diabetes, inflammations and cancer …