Hypercholesterolemia is a major risk factor for cardiovascular disease. Cholesterol
homeostasis in the body is governed by the interplay between absorption, synthesis, and …

Maternal undernutrition or overnutrition during pregnancy alters organ structure, impairs
prenatal and neonatal growth and development, and reduces feed efficiency for lean tissue …

Non-alcoholic fatty liver disease (NAFLD) is one of the first hepatic manifestations of
metabolic syndrome, whose progression can lead to cirrhosis and hepatic carcinoma …

The placenta is particularly susceptible to inflammation and oxidative stress, leading to
placental vascular dysfunction and placental insufficiency, which is associated with fetal …

Maternal dietary patterns during pregnancy have been demonstrated to impact the structure
of the gut microbiota in offspring, altering their susceptibility to diseases. This study is …

Recent findings from human and animal studies indicate that maternal undernutrition or
overnutrition affects covalent modifications of the fetal genome and its associated histones …

Maternal folic acid (FA) supplementation is well recognised to protect against neural tube
defects. Folate is a critical cofactor in one-carbon metabolism involved in the epigenetic …

Little is known if and how maternal diet affects the liver phospholipid profiles that contribute
to non-alcoholic fatty liver disease (NAFLD) development in offspring. We examined NAFLD …

The placental metabolism can adapt to the environment throughout pregnancy to both the
demands of the fetus and the signals from the mother. Such adaption processes include …

Maternal obesity increases fetal adiposity which may adversely affect metabolic health of the
offspring. Choline regulates lipid metabolism and thus may influence adiposity. This study …