The ultimate goal of most biomedical research is to gain greater insight into mechanisms of
human disease or to develop new and improved therapies or diagnostics. Although great …

Cell cultures are widely used in pharmaceutical, medical, food/nutrition and biological
sciences. In food and nutrition science, intestinal cell culture models of human origin are …

A human gut-on-a-chip microdevice was used to coculture multiple commensal microbes in
contact with living human intestinal epithelial cells for more than a week in vitro and to …

Development of an in vitro living cell-based model of the intestine that mimics the
mechanical, structural, absorptive, transport and pathophysiological properties of the human …

Adjuvant 5-fluorouracil (5-FU)-based chemotherapy, including FOLFOX (5-FU, leucovorin,
and oxaliplatin), is recommended for colorectal cancer. However, intestinal mucositis …

Background and Aims Intestinal mucositis is a frequently encountered side effect in
oncology patients undergoing chemotherapy. No well-established or up to date therapeutic …

The influence of microbiota in human health is well-known. Imbalances in microbiome
structure have been linked to several diseases. Modulation of microbiota composition …

Objective In recent years, a great number of studies have been directed toward the
evaluation of gastrointestinal microbiota modulation through the introduction of beneficial …

Oral exposure to nanomaterials is a current concern, asking for innovative biological test
systems to assess their safety, especially also in conditions of inflammatory disorders. Aim of …

The gut microbiome has been known to contribute up to~ 30% of the energy absorption of
the host. Although various beneficial mechanisms of probiotics have been suggested for non …