Despite the advent of new diagnostics, drugs and regimens, tuberculosis (TB) remains a
global public health threat. A significant challenge for TB control efforts has been the …

Tuberculosis (TB) drug discovery and development has undergone nothing short of a
revolution over the past 20 years. Successful public–private partnerships and sustained …

Guidelines on the treatment of tuberculosis (TB) have essentially remained the same for the
past 35 years, but are now starting to change. Ongoing clinical trials will hopefully transform …

Imperfect medication adherence remains the biggest predictor of treatment failure for
patients with tuberculosis. Missed doses during treatment lead to relapse, tuberculosis …

Background Direct bronchial spread of tuberculosis was extensively described in pre-
antibiotic human pathology literature but this description has been overlooked in the post …

Background There is a growing interest in the use of F-18 FDG PET-CT to monitor
tuberculosis (TB) treatment response. Tuberculosis lung lesions are often complex and …

Nearly 140 years after Robert Koch discovered Mycobacterium tuberculosis, tuberculosis
(TB) remains a global threat and a deadly human pathogen. M. tuberculosis is notable for …

Tuberculosis (TB) remains a leading infectious cause of death worldwide and the
coronavirus disease 2019 pandemic has negatively impacted the global TB burden of …

Untreated active tuberculosis (TB) has a very high long-term mortality. Treatment of TB
reduces mortality dramatically and should maximize cure, preventing ongoing transmission …

Positron emission tomography–computed tomography (PET-CT) has the potential to
revolutionize research in infectious diseases, as it has done with cancer. There is growing …