Cationic host defence peptides (CHDP), also known as antimicrobial peptides, are naturally
occurring peptides that can combat infections through their direct microbicidal properties …

Host defence peptides (HDPs) are integral components of innate immunity across all living
organisms. These peptides can exert direct antibacterial effects, targeting planktonic cells …

Current research has demonstrated that small cationic amphipathic peptides have strong
potential not only as antimicrobials, but also as antibiofilm agents, immune modulators, and …

Although first studied for their antimicrobial activity, host defense peptides (HDPs) are now
widely recognized for their multifunctional roles in both the innate and adaptive immune …

Cationic host defense (antimicrobial) peptides were originally studied for their direct
antimicrobial activities. They have since been found to exhibit multifaceted …

Bacteria form multicellular communities known as biofilms that cause two thirds of all
infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional …

The growth of bacteria as structured aggregates termed biofilms leads to their protection
from harsh environmental conditions such as physical and chemical stresses, shearing …

The growing number of bacterial pathogens that are resistant to numerous antibiotics is a
cause for concern around the globe. There have been no new broad‐spectrum antibiotics …

The increasing prevalence of multidrug-resistant bacterial infections necessitates the
exploration of novel paradigms for anti-infective therapy. Antimicrobial peptides (AMPs), also …

Mycobacterium tuberculosis (Mtb) is one of the most important infectious agents worldwide
and causes more than 1.5 million deaths annually. To make matters worse, the drug …