Abstract Circular RNAs (CircRNAs) are non-coding RNAs (ncRNAs) characterized by a
stable circular structure that regulates gene expression at both transcriptional and post …

Simple Summary Patients with gliomas experience worsened quality of life due to epileptic
attacks. Over 80% of patients are susceptible to seizures, significantly hindering their …

Abstract Salvigenin is a Trimethoxylated Flavone enriched in Scutellariae Barbatae Herba
and Scutellariae Radix and is demonstrated to have anti-tumor properties in colon cancer …

The tumor suppressor PTEN (phosphatase and tensin homolog deleted in chromosome 10)
is genetically deleted or downregulated in many cancer types. Loss of PTEN protein …

Tumor suppressor p53 can transcriptionally activate downstream genes in response to
stress, and then regulate the cell cycle, DNA repair, metabolism, angiogenesis, apoptosis …

Glioblastoma (GBM), one of the most aggressive forms of brain cancer, has limited treatment
options. Recent years have witnessed the remarkable success of checkpoint inhibitor …

As the pioneering study from Pakistan, our research distinctly focuses on validating the roles
of autophagy-associated genes and MicroRNAs (miRs) in the unique context of our …

Glioblastoma (GB) is a highly heterogeneous type of incurable brain cancer with a low
survival rate. Intensive ongoing research has identified several potential targets; however …

The global challenge posed by cancer, marked by rising incidence and mortality rates,
underscores the urgency for innovative therapeutic approaches. The PI3K/Akt signaling …

In addition to environmental conditions, lifestyle factors, and chemical exposure, aberrant
gene expression and mutations involve in the beginning and development of urological …