Telomeres are dynamic nucleoprotein-DNA structures that cap and protect linear
chromosome ends. Because telomeres shorten progressively with each replication, they …

Reactive oxygen species (ROS) have long been considered as pathological agents
inducing apoptosis under adverse culture conditions. However, recent findings have …

The effects of healthy aging on the kidney, and how these effects intersect with
superimposed diseases, are highly relevant in the context of the population's increasing …

Nicotinamide adenine dinucleotide (oxidized form, NAD+) is a critical coenzyme, with
functions ranging from redox reactions and energy metabolism in mitochondrial respiration …

Inflammation is a physiologic component of pregnancy and parturition. Overwhelming
intrauterine inflammatory load promotes quiescent feto‐maternal tissues into a contractile …

Oxidative stress (OS)-induced senescence of the amniochorion has been associated with
parturition at term. We investigated whether telomere fragments shed into the amniotic fluid …

Problem We investigated p38 MAPK activation‐induced fetal membrane cell senescence in
response to inflammation (tumour necrosis factor‐alpha [TNF‐α]) and infection …

Mesenchymal stem cells (MSCs) are earmarked as perfect candidates for cell therapy and
tissue engineering due to their capacity to differentiate into different cell types. However …

Stem cell‐based cellular therapy is a promising tool for the treatment of pathological
conditions with underlying severe tissue damage or malfunction like in chronic …

Introduction Ultra-short telomeres caused by stress-induced telomere shortening are
suggested to induce chondrocyte senescence in human osteoarthritic knees. Here we have …