Intervertebral disc degeneration (IVDD) has been the major contributor to chronic lower back
pain (LBP). Abnormal apoptosis, senescence, and pyroptosis of IVD cells, extracellular …

Degenerative disc disease is a common manifestation in routine imaging of the spine; this
finding is partly attributable to physiological aging and partly to a pathological condition, and …

Low back pain is a major public health concern experienced by 80% of the world's
population during their lifetime, which is closely associated with intervertebral disc (IVD) …

Low back pain is a vital musculoskeletal disease that impairs life quality, leads to disability
and imposes heavy economic burden on the society, while it is greatly attributed to …

Through years of evolution, biological soft fibrous tissues have developed remarkable
functional properties, unique hierarchical architectures, and-most notably, an unparalleled …

Due to the complicated structure of the elastic fiber network in annulus fibrosus, existing in-
silico studies either simplified or just overlooked its distribution pattern. Nonetheless …

In the present article, a fully three-dimensional human annulus fibrosus model is developed
by considering the regional variation of the complex structural organization of collagen …

Artificial nucleus pulposus (ANP) replacement as an alternative to the treatment of cervical
spondylosis aims to relieve pain and restore the normal cervical motion. In this study, the …

Despite extensive efforts over the past 40 years, there is still a significant gap in knowledge
of the characteristics of elastic fibers in the intervertebral disc (IVD). More studies are …

Mechanical properties of blood clots play a crucial role in hemostasis and embolization.
They are time-dependent and often described with viscoelastic models. But blood clots also …