Aspergillus fumigatus and Aspergillosis in 2019

JP Latgé, G Chamilos - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Aspergillus fumigatus is a saprotrophic fungus; its primary habitat is the soil. In its ecological
niche, the fungus has learned how to adapt and proliferate in hostile environments. This …

[HTML][HTML] Fungal iron homeostasis with a focus on Aspergillus fumigatus

M Misslinger, P Hortschansky, AA Brakhage… - Biochimica et Biophysica …, 2021 - Elsevier
To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …

Fungal siderophore metabolism with a focus on Aspergillus fumigatus: impact on biotic interactions and potential translational applications

I Happacher, M Aguiar, A Yap… - Essays in …, 2023 - portlandpress.com
Iron is an essential trace element that is limiting in most habitats including hosts for fungal
pathogens. Siderophores are iron-chelators synthesized by most fungal species for high …

HapX, an indispensable bZIP transcription factor for iron acquisition, regulates infection initiation by orchestrating conidial oleic acid homeostasis and cytomembrane …

YJ Peng, JJ Wang, HY Lin, JL Ding, MG Feng… - Msystems, 2020 - Am Soc Microbiol
In pathogenic filamentous fungi, conidial germination not only is fundamental for
propagation in the environment but is also a critical step of infection. In the insect …

Aspergillus fumigatus Elongator complex subunit 3 affects hyphal growth, adhesion and virulence through wobble uridine tRNA modification

Y Zhang, Y Wang, J Fan, G Zhu, L Lu - Plos Pathogens, 2022 - journals.plos.org
The eukaryotic multisubunit Elongator complex has been shown to perform multiple
functions in transcriptional elongation, histone acetylation and tRNA modification. However …

Regulatory and pathogenic mechanisms in response to iron deficiency and excess in fungi

J Pijuan, DF Moreno, G Yahya, M Moisa… - Microbial …, 2023 - Wiley Online Library
Iron is an essential element for all eukaryote organisms because of its redox properties,
which are important for many biological processes such as DNA synthesis, mitochondrial …

[HTML][HTML] Adaptation to iron deficiency in human pathogenic fungi

MT Martínez-Pastor, S Puig - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Iron is an essential micronutrient for virtually all eukaryotic organisms and plays a central
role during microbial infections. Invasive fungal diseases are associated with strikingly high …

Galleria mellonella as a screening tool to study virulence factors of Aspergillus fumigatus

MF Durieux, É Melloul, S Jemel, L Roisin, ML Dardé… - Virulence, 2021 - Taylor & Francis
The invertebrate Galleria mellonella has increasingly and widely been used in the last few
years to study complex host–microbe interactions. Aspergillus fumigatus is one of the most …

RETRACTED: Huaier extract suppresses non‐small cell lung cancer progression through activating NLRP3‐dependent pyroptosis

J Xie, B Zhuan, H Wang, Y Wang, X Wang… - The Anatomical …, 2021 - Wiley Online Library
Recent studies have reported the anticancer activity of huaier extract in various human
malignancies. However, little is known about the effect of huaier extract in non‐small cell …

Transcription factors SltA and CrzA reversely regulate calcium homeostasis under calcium-limited conditions

M Dai, W Du, L Lu, S Zhang - Applied and Environmental …, 2023 - Am Soc Microbiol
The maintenance of cellular calcium homeostasis in response to calcium supply is required
for a wide range of physiological processes in fungi, including growth, development, and …