The future of cancer vaccines against colorectal cancer

W Jia, X Shen, Z Guo, X Cheng… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Colorectal cancer (CRC) is the second most lethal malignancy worldwide.
Immune checkpoint inhibitors (ICIs) benefit only 15% of patients with mismatch repair …

Designing of a multi-epitopes based vaccine against Haemophilius parainfluenzae and its validation through integrated computational approaches

SA Ghaffar, H Tahir, S Muhammad, M Shahid… - Frontiers in …, 2024 - frontiersin.org
Haemophilus parainfluenzae is a Gram-negative opportunist pathogen within the mucus of
the nose and mouth without significant symptoms and has an ability to cause various …

Designing a novel multi-epitopes pan-vaccine against SARS-CoV-2 and seasonal influenza: in silico and immunoinformatics approach

M Fathollahi, H Motamedi, H Hossainpour… - Journal of …, 2024 - Taylor & Francis
The merger of COVID-19 and seasonal influenza infections is considered a potentially
serious threat to public health. These two viral agents can cause extensive and severe lower …

In silico design of a novel multi-epitope vaccine against HCV infection through immunoinformatics approaches

S Ahmad, FM Demneh, B Rehman, TN Almanaa… - International Journal of …, 2024 - Elsevier
Infection with the hepatitis C virus (HCV) is one of the causes of liver cancer, which is the
world's sixth most prevalent and third most lethal cancer. The current treatments do not …

Subtractive Proteomics and Reverse-Vaccinology Approaches for Novel Drug Target Identification and Chimeric Vaccine Development against Bartonella henselae …

S Rahman, CC Chiou, S Ahmad, ZU Islam, T Tanaka… - Bioengineering, 2024 - mdpi.com
Bartonella henselae is a Gram-negative bacterium causing a variety of clinical symptoms,
ranging from cat-scratch disease to severe systemic infections, and it is primarily transmitted …

[HTML][HTML] Fusobacterium nucleatum-induced imbalance in microbiome-derived butyric acid levels promotes the occurrence and development of colorectal cancer

QL Wu, XT Fang, XX Wan, QY Ding… - World Journal of …, 2024 - ncbi.nlm.nih.gov
BACKGROUND Colorectal cancer (CRC) ranks among the most prevalent malignant tumors
globally. Recent reports suggest that Fusobacterium nucleatum (F. nucleatum) contributes to …

[HTML][HTML] Isolation, characterization, and experimental infection of Streptococcus gallolyticus subspecies pasteurianus from commercial turkeys with acute septicemia: a …

LS Gray, JD Latorre, D Hernandez-Patlan, B Solis-Cruz… - Poultry Science, 2023 - Elsevier
Streptococcus gallolyticus (SG) is a Gram-positive cocci found as commensal gut flora in
animals and humans. SG has emerged as a cause of disease in young poults between 1 …

[HTML][HTML] Identifying therapeutic effect of kombucha Pirdot (Saurauia vulcani Korth.) against colorectal cancer: The experimental data and in silico approach

E Sinaga, U Hasanah, FRP Sipahutar… - Medicine in …, 2024 - Elsevier
This study pioneers the evaluation of Kombucha Pirdot (KP) in combating colorectal cancer
through combined in vivo and in silico methods. It involved categorizing rats into four groups …

BLAB2CancerKD: a knowledge graph database focusing on the association between lactic acid bacteria and cancer, but beyond

Y Jing, B Feng, J Gao, J Li, G Zhou, Z Sun, Y Wang - Database, 2023 - academic.oup.com
In a broad sense, lactic acid bacteria (LAB) is a general term for Gram-positive bacteria that
can produce lactic acid by utilizing fermentable carbohydrates. It is widely used in essential …

Advancing Tolerogenic Immunotherapy: A Multi-Epitope Vaccine Design Targeting the CYP2D6 Autoantigen in Autoimmune Hepatitis Through Immuno-Informatics

HB Kolla, A Kumar, RH Nanjunadappa, B Hilyard… - bioRxiv, 2024 - biorxiv.org
Juvenile autoimmune hepatitis (JAIH) is a rare autoimmune disorder affecting children,
characterized by the immune system's misguided attack on liver cells, primarily targeting the …