T cell responses to SARS-CoV-2

A Sette, J Sidney, S Crotty - Annual review of immunology, 2023 - annualreviews.org
A large body of evidence generated in the last two and a half years addresses the roles of T
cells in SARS-CoV-2 infection and following vaccination. Infection or vaccination induces …

Durability of vaccine-induced and natural immunity against COVID-19: a narrative review

N Pooley, SS Abdool Karim, B Combadière… - Infectious Diseases and …, 2023 - Springer
Vaccines developed against SARS-CoV-2 have proven to be highly effective in preventing
symptomatic infection. Similarly, prior infection with SARS-CoV-2 has been shown to provide …

[HTML][HTML] Variations within the glycan shield of SARS-CoV-2 impact viral spike dynamics

ML Newby, CA Fogarty, JD Allen, J Butler… - Journal of Molecular …, 2023 - Elsevier
The emergence of SARS-CoV-2 variants alters the efficacy of existing immunity, whether
arisen naturally or through vaccination. Understanding the structure of the viral spike assists …

[HTML][HTML] Epidemiological and clinical perspectives of long COVID syndrome

K Huerne, KB Filion, R Grad, P Ernst… - American Journal of …, 2023 - Elsevier
Long COVID, or post-acute COVID-19 syndrome, is characterized by multi-organ symptoms
lasting 2+ months after initial COVID-19 virus infection. This review presents the current state …

Differences in humoral and cellular vaccine responses to SARS-CoV-2 in kidney and liver transplant recipients

L Furian, FP Russo, G Zaza, P Burra, S Hartzell… - Frontiers in …, 2022 - frontiersin.org
The antibody and T cell responses after SARS-CoV-2 vaccination have not been formally
compared between kidney and liver transplant recipients. Using a multiplex assay, we …

Immunogenicity evaluation after BNT162b2 booster vaccination in healthcare workers

S Zurac, C Vladan, O Dinca, C Constantin, M Neagu - Scientific Reports, 2022 - nature.com
Waning of the immune response upon vaccination in SARS-CoV-2 infection is an important
subject of evaluation in this pandemic, mostly in healthcare workers (HCW) that are …

Dynamics of antibody and T cell immunity against SARS-CoV-2 variants of concern and the impact of booster vaccinations in previously infected and infection-naïve …

MR Faas, WA Mak, HY Markus, EM van der Zwan… - Vaccines, 2022 - mdpi.com
Despite previous coronavirus disease 2019 (COVID-19) vaccinations and severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, SARS-CoV-2 still causes a …

Complete (humoral and cellular) response to vaccination against COVID-19 in a group of healthcare workers-assessment of factors affecting immunogenicity

E Morgiel, M Szmyrka, M Madej, A Sebastian… - Vaccines, 2022 - mdpi.com
Vaccination is the best way to limit the extent of the COVID pandemic. Knowledge of the
duration of the immune response will allow the planning of a vaccination protocol. This study …

Interim safety and immunogenicity analysis of the EuCorVac‐19 COVID‐19 vaccine in a Phase 3 randomized, observer‐blind, immunobridging trial in the Philippines

JF Lovell, K Miura, YO Baik, C Lee… - Journal of Medical …, 2024 - Wiley Online Library
Abstract EuCorVac‐19 (ECV‐19) is a recombinant receptor binding domain (RBD) COVID‐
19 vaccine that displays the RBD (derived from the SARS‐CoV‐2 Wuhan strain) on …

Measuring T-cell responses against SARS-CoV-2 is of utility for disease and vaccination management

G Safont, I Latorre, R Villar-Hernández… - Journal of clinical …, 2022 - mdpi.com
The measurement of specific T-cell responses can be a useful tool for COVID-19 diagnostics
and clinical management. In this study, we evaluated the IFN-γ T-cell response against the …