Genome-wide association studies (GWAS) identify genetic variants that distinguish a control
population from a population with a specific trait. Two challenges in GWAS are:(1) …

Background Gene expression is a key intermediate level that genotypes lead to a particular
trait. Gene expression is affected by various factors including genotypes of genetic variants …

Gene expression is a critical process in biological system that is influenced and modulated
by many factors including genetic variation. Expression Quantitative Trait Loci (eQTL) …

Plant carotenoids have a key role in preventing various diseases in human because of their
antioxidant and provitamin A properties. Chickpea is a good source of carotenoid among …

Mitochondrial DNA (mtDNA) variants have been traditionally used as markers to trace
ancient population migrations. Although experiments relying on model organisms and …

Copy number variants (CNVs) refer to the loss or gain of copies of a genomic DNA region.
While some CNVs may play a role in species evolution by enriching the diversity of an …

Associations between the level of single transcripts and single corresponding genetic
variants, expression single nucleotide polymorphisms (eSNPs), have been extensively …

Mapping regulatory variants is a powerful approach for identifying the underlying biological
mechanisms that define heritable phenotypes. Although each individual carries two copies …

Hormon i adipocitokin leptin (LEP) moţe učestvovati u patogenezi multiple skleroze (MS)
delovanjem na produkciju potentnog proinflamatornog citokina, TNF-α, aktivnost …

■ This thesis includes the following publications that I was the primary author of.–The
content of chapter 3 appears in this publication: Ziad Al Bkhetan, Justin Zobel, Adam …