Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …

Biomedical research is undergoing a paradigm shift towards approaches centred on human
disease models owing to the notoriously high failure rates of the current drug development …

Tissue damage and inflammation are important triggers for regeneration and fibrosis. Tissue
damage not only induces inflammation in general, it also determines the type and …

The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

Background: Atopic dermatitis (AD) is a common inflammatory skin disease with complex
pathogenesis. Natural flavonoids exhibit strong anti-inflammatory and antioxidant properties …

To advance drug development representative reliable skin models are indispensable.
Animal skin as test model for human skin delivery is restricted as their properties greatly …

The skin is the first line of defense of our body, and it is composed of the epidermis and
dermis with diverse immune cells. Various in vitro models have been investigated to …

Sažetak There is an increasing number of experimental, genetic and clinical evidence of
atopic dermatitis expression as a pre-condition for later development of other atopic …

Atopic dermatitis (AD) is a common, chronic, inflammatory skin condition characterized by
recurrent and pruritic skin eruptions. Multiple factors contribute to the pathogenesis of AD …

Atopic diseases refer to common allergic inflammatory diseases such as atopic dermatitis
(AD), allergic rhinitis (AR), and allergic asthma (AA). AD often develops in early childhood …