[HTML][HTML] Cell fate decisions, transcription factors and signaling during early retinal development

R Diacou, P Nandigrami, A Fiser, W Liu… - Progress in retinal and …, 2022 - Elsevier
The development of the vertebrate eyes is a complex process starting from anterior-posterior
and dorso-ventral patterning of the anterior neural tube, resulting in the formation of the eye …

Pathogenesis of pituitary tumors

S Melmed - Nature Reviews Endocrinology, 2011 - nature.com
Pituitary adenomas may hypersecrete hormones (including prolactin, growth hormone and
adrenocorticotropic hormone, and rarely follicle-stimulating hormone, luteinizing hormone or …

Single-cell transcriptomics identifies divergent developmental lineage trajectories during human pituitary development

S Zhang, Y Cui, X Ma, J Yong, L Yan, M Yang… - Nature …, 2020 - nature.com
The anterior pituitary gland plays a central role in regulating various physiological
processes, including body growth, reproduction, metabolism and stress response. Here, we …

Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis

X Li, KA Ohgi, J Zhang, A Krones, KT Bush, CK Glass… - Nature, 2003 - nature.com
The precise mechanistic relationship between gene activation and repression events is a
central question in mammalian organogenesis, as exemplified by the evolutionarily …

Specification of the vertebrate eye by a network of eye field transcription factors

ME Zuber, G Gestri, AS Viczian, G Barsacchi… - 2003 - journals.biologists.com
Several eye-field transcription factors (EFTFs) are expressed in the anterior region of the
vertebrate neural plate and are essential for eye formation. The Xenopus EFTFs ET, Rx1 …

Genetic regulation of pituitary gland development in human and mouse

D Kelberman, K Rizzoti, R Lovell-Badge… - Endocrine …, 2009 - academic.oup.com
Normal hypothalamopituitary development is closely related to that of the forebrain and is
dependent upon a complex genetic cascade of transcription factors and signaling molecules …

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors

V Perissi, A Aggarwal, CK Glass, DW Rose… - Cell, 2004 - cell.com
The mechanisms that control the precisely regulated switch from gene repression to gene
activation represent a central question in mammalian development. Here, we report that …

Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes

SD Moorthy, S Davidson, VM Shchuka… - Genome …, 2017 - genome.cshlp.org
Transcriptional enhancers are critical for maintaining cell-type–specific gene expression and
driving cell fate changes during development. Highly transcribed genes are often associated …

Major review: Molecular genetics of primary open-angle glaucoma

Y Liu, RR Allingham - Experimental eye research, 2017 - Elsevier
Glaucoma is a leading cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), the most common type, is a complex inherited disorder that is …

[HTML][HTML] Induction and specification of cranial placodes

G Schlosser - Developmental biology, 2006 - Elsevier
Cranial placodes are specialized regions of the ectoderm, which give rise to various sensory
ganglia and contribute to the pituitary gland and sensory organs of the vertebrate head …