TH17 cell heterogeneity and its role in tissue inflammation

A Schnell, DR Littman, VK Kuchroo - Nature immunology, 2023 - nature.com
Since their discovery almost two decades ago, interleukin-17-producing CD4+ T cells (TH17
cells) have been implicated in the pathogenesis of multiple autoimmune and inflammatory …

Immune mechanisms in oral lichen planus

A El‐Howati, MH Thornhill, HE Colley… - Oral diseases, 2023 - Wiley Online Library
Oral lichen planus (OLP) is a T cell‐mediated inflammatory disease of the oral mucosa that
has been extensively researched over many years but as yet the mechanisms of …

Atherosclerosis and inflammation: Insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Photodynamic therapy and immunity: an update

R Falk‐Mahapatra, SO Gollnick - Photochemistry and …, 2020 - Wiley Online Library
Abstract Dr. Thomas Dougherty and his Oncology Foundation of Buffalo were the first to
support my (SOG) research into the effects of photodynamic therapy (PDT) on the host …

Inflammation: A new look at an old problem

E Gusev, Y Zhuravleva - International Journal of Molecular Sciences, 2022 - mdpi.com
Pro-inflammatory stress is inherent in any cells that are subject to damage or threat of
damage. It is defined by a number of universal components, including oxidative stress …

Hallmarks of immune response in COVID-19: Exploring dysregulation and exhaustion

A Mazzoni, L Salvati, L Maggi, F Annunziato… - Seminars in …, 2021 - Elsevier
One and half year following the occurrence of COVID-19 pandemic, significant efforts from
laboratories all over the world generated a huge amount of data describing the prototypical …

[HTML][HTML] Th17 cells in periodontitis and its regulation by A20

N Huang, H Dong, Y Luo, B Shao - Frontiers in immunology, 2021 - frontiersin.org
Periodontitis is a prevalent chronic disease that results in loss of periodontal ligament and
bone resorption. Triggered by pathogens and prolonged inflammation, periodontitis is …

The conundrum of lung disease and drug hypersensitivity‐like reactions in systemic juvenile idiopathic arthritis

BA Binstadt, PA Nigrovic - Arthritis & rheumatology, 2022 - Wiley Online Library
An unusual form of lung disease has begun to affect some children with systemic juvenile
idiopathic arthritis (JIA), coincident with increasing utilization of interleukin‐1 (IL‐1) and IL‐6 …

Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis

GR Burmester, ME Weinblatt, IB McInnes… - Annals of the …, 2013 - ard.bmj.com
Objectives Mavrilimumab, a human monoclonal antibody targeting the alpha subunit of the
granulocyte-macrophage colony-stimulating factor receptor, was evaluated in a phase 2 …