Airway remodeling in asthma
KP Hough, ML Curtiss, TJ Blain, RM Liu, J Trevor… - Frontiers in …, 2020 - frontiersin.org
Asthma is an inflammatory disease of the airways that may result from exposure to allergens
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …
or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of …
Remodeling in asthma
S Al-Muhsen, JR Johnson, Q Hamid - Journal of allergy and clinical …, 2011 - Elsevier
Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
normal airways. Airway remodeling in asthmatic patients involves a wide array of …
Uniform definition of asthma severity, control, and exacerbations: document presented for the World Health Organization Consultation on Severe Asthma
J Bousquet, E Mantzouranis, AA Cruz… - Journal of Allergy and …, 2010 - Elsevier
Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic
groups and countries. It is estimated that around 250,000 people die prematurely each year …
groups and countries. It is estimated that around 250,000 people die prematurely each year …
Airway remodeling heterogeneity in asthma and its relationship to disease outcomes
A Hsieh, N Assadinia, TL Hackett - Frontiers in physiology, 2023 - frontiersin.org
Asthma affects an estimated 262 million people worldwide and caused over 461,000 deaths
in 2019. The disease is characterized by chronic airway inflammation, reversible …
in 2019. The disease is characterized by chronic airway inflammation, reversible …
Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report
LB Bacharier, A Boner, KH Carlsen, PA Eigenmann… - Allergy, 2008 - Wiley Online Library
Asthma is the leading chronic disease among children in most industrialized countries.
However, the evidence base on specific aspects of pediatric asthma, including therapeutic …
However, the evidence base on specific aspects of pediatric asthma, including therapeutic …
Pediatric severe asthma is characterized by eosinophilia and remodeling without TH2 cytokines
BACKGROUND: The pathology of pediatric severe therapy-resistant asthma (STRA) is little
understood. OBJECTIVES: We hypothesized that STRA in children is characterized by …
understood. OBJECTIVES: We hypothesized that STRA in children is characterized by …
IL-33 promotes airway remodeling in pediatric patients with severe steroid-resistant asthma
S Saglani, S Lui, N Ullmann, GA Campbell… - Journal of allergy and …, 2013 - Elsevier
Background TH 2 cytokines are not responsible for the ongoing symptoms and pathology in
children with severe therapy-resistant asthma (STRA). IL-33 induces airway …
children with severe therapy-resistant asthma (STRA). IL-33 induces airway …
Early detection of airway wall remodeling and eosinophilic inflammation in preschool wheezers
Rationale: It is unclear when the pathologic features of asthma first appear. We
hypothesized that eosinophilic airway inflammation and epithelial reticular basement …
hypothesized that eosinophilic airway inflammation and epithelial reticular basement …
Mild asthma: an expert review on epidemiology, clinical characteristics and treatment recommendations
This review is the synthesis of a working group on mild asthma. Mild asthma includes
intermittent and persistent mild asthma according to the Global Initiative for Asthma (GINA) …
intermittent and persistent mild asthma according to the Global Initiative for Asthma (GINA) …
Airway remodeling and inflammation in symptomatic infants with reversible airflow obstruction
S Saglani, K Malmström, AS Pelkonen… - American journal of …, 2005 - atsjournals.org
Rationale: We hypothesized that the epithelial reticular basement membrane (RBM)
thickening and eosinophilic inflammation characteristic of asthma would be present in …
thickening and eosinophilic inflammation characteristic of asthma would be present in …