Breast cancer develops in the mammary glands during mammalian adulthood and is
considered the second most common type of human carcinoma and the most incident and …

Hox genes encode homeodomain transcription factors that control morphogenesis and have
established functions in development and evolution. Hox proteins have remained enigmatic …

HOTAIRM1 is a long intergenic non-coding RNA encoded in the human HOXA gene cluster,
with gene expression highly specific for maturing myeloid cells. Knockdown of HOTAIRM1 in …

Abstract Development of drug resistance is a major factor limiting the continued success of
cancer chemotherapy. To overcome drug resistance, understanding the underlying …

The characteristics of mesenchymal stromal cells (MSCs) which derived from multiple
myeloma (MM) patients are typically impaired in osteogenic differentiation. However, the …

The filamentous fungus Sordaria macrospora is a model system to study multicellular
development during fruiting body formation. Previously, we demonstrated that this major …

The RecQL4 helicase is involved in the maintenance of genome integrity and DNA
replication. Mutations in the human RecQL4 gene cause the Rothmund–Thomson …

Abstract hox genes encode a conserved family of homeodomain transcription factors that
are essential to determine the identity of body segments during embryogenesis and …

Hox proteins are conserved homeodomain transcription factors involved in the control of
embryo patterning, organ development, and cell differentiation during animal development …

Abstract Phospholipases A2 (PLA2) are a superfamily of enzymes, playing a critical role in
the development of various human cancers. However, the mechanism of PLA2 as an …