Spinal cord transcutaneous stimulation in cervical spinal cord injury: A review examining upper extremity neuromotor control, recovery mechanisms, and future …

G Singh, P Sharma, G Forrest, S Harkema… - Journal of …, 2024 - liebertpub.com
Cervical spinal cord injury (SCI) results in significant sensorimotor impairments below the
injury level, notably in the upper extremities (UEs), impacting daily activities and quality of …

Multi-site spinal cord transcutaneous stimulation facilitates upper limb sensory and motor recovery in severe cervical spinal cord injury: a case study

P Sharma, T Panta, B Ugiliweneza, RJ Bert… - Journal of Clinical …, 2023 - mdpi.com
Individuals with cervical spinal cord injury (SCI) rank regaining arm and hand function as
their top rehabilitation priority post-injury. Cervical spinal cord transcutaneous stimulation …

When spinal neuromodulation meets sensorimotor rehabilitation: Lessons learned from animal models to regain manual dexterity after a spinal cord injury

Á Flores, D López-Santos… - Frontiers in Rehabilitation …, 2021 - frontiersin.org
Electrical neuromodulation has strongly hit the foundations of spinal cord injury and repair.
Clinical and experimental studies have demonstrated the ability to neuromodulate and …

Preservation of functional descending input to paralyzed upper extremity muscles in motor complete cervical spinal cord injury

P Sharma, A Naglah, S Aslan, F Khalifa, A El-Baz… - Clinical …, 2023 - Elsevier
Objective Spinal cord injury (SCI) is classified as complete or incomplete depending on the
extent of sensorimotor preservation below the injury level. However, individuals with …

Glassy carbon neural interface for chronic epidural stimulation in rats with cervical spinal cord injury

S Samejima, R Hanna, BK Cariappa… - … on Neural Systems …, 2022 - ieeexplore.ieee.org
There is growing evidence on the efficacy of electrical stimulation delivered via spinal neural
interfaces to improve functional recovery following spinal cord injury. For such interfaces …

Novel comprehensive analysis of skilled reaching and grasping behavior in adult rats

P Sharma, Y Du, K Singapuri, DM Delafraz… - Journal of Neuroscience …, 2024 - Elsevier
Background Reaching and grasping (R&G) in rats is commonly used as an outcome
measure to investigate the effectiveness of rehabilitation or treatment strategies to recover …

Intraoperative electrical stimulation of the human dorsal spinal cord reveals a map of arm and hand muscle responses

JR McIntosh, EF Joiner, JL Goldberg… - Journal of …, 2023 - journals.physiology.org
Although epidural stimulation of the lumbar spinal cord has emerged as a powerful modality
for recovery of movement, how it should be targeted to the cervical spinal cord to activate …

Repeated epidural stimulation modulates cervical spinal cord excitability in healthy adult rats

P Sharma, H Rampersaud, PK Shah - Experimental Brain Research, 2025 - Springer
Spinal evoked motor responses (SEMR) are utilized in longitudinal pre-clinical and human
studies to reflect the in-vivo physiological changes in neural networks secondary to a spinal …

Tuning of motor outputs produced by spinal stimulation during voluntary control of torque directions in monkeys

M Kaneshige, K Obara, M Suzuki, T Tazoe… - Elife, 2022 - elifesciences.org
Spinal stimulation is a promising method to restore motor function after impairment of
descending pathways. While paresis, a weakness of voluntary movements driven by …

Transcutaneous spinal stimulation in people with and without spinal cord injury: Effect of electrode placement and trains of stimulation on threshold intensity

HT Finn, EA Bye, TG Elphick… - Physiological …, 2023 - Wiley Online Library
Transcutaneous spinal cord stimulation (TSS) is purported to improve motor function in
people after spinal cord injury (SCI). However, several methodology aspects are yet to be …