Hippocampal GABAergic inhibitory interneurons
KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …
of the total neuronal population; however, their remarkable anatomical and physiological …
Molecular logic of neocortical projection neuron specification, development and diversity
LC Greig, MB Woodworth, MJ Galazo… - Nature Reviews …, 2013 - nature.com
The sophisticated circuitry of the neocortex is assembled from a diverse repertoire of
neuronal subtypes generated during development under precise molecular regulation. In …
neuronal subtypes generated during development under precise molecular regulation. In …
Molecular logic of cellular diversification in the mouse cerebral cortex
The mammalian cerebral cortex has an unparalleled diversity of cell types, which are
generated during development through a series of temporally orchestrated events that are …
generated during development through a series of temporally orchestrated events that are …
Proper acquisition of cell class identity in organoids allows definition of fate specification programs of the human cerebral cortex
Realizing the full utility of brain organoids to study human development requires
understanding whether organoids precisely replicate endogenous cellular and molecular …
understanding whether organoids precisely replicate endogenous cellular and molecular …
Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia
The human cortex comprises diverse cell types that emerge from an initially uniform
neuroepithelium that gives rise to radial glia, the neural stem cells of the cortex. To …
neuroepithelium that gives rise to radial glia, the neural stem cells of the cortex. To …
Genetic dissection of the glutamatergic neuron system in cerebral cortex
Diverse types of glutamatergic pyramidal neurons mediate the myriad processing streams
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
and output channels of the cerebral cortex,, yet all derive from neural progenitors of the …
Voltage imaging and optogenetics reveal behaviour-dependent changes in hippocampal dynamics
A technology that simultaneously records membrane potential from multiple neurons in
behaving animals will have a transformative effect on neuroscience research,. Genetically …
behaving animals will have a transformative effect on neuroscience research,. Genetically …
Human iPSC-derived cerebral organoids model cellular features of lissencephaly and reveal prolonged mitosis of outer radial glia
M Bershteyn, TJ Nowakowski, AA Pollen, E Di Lullo… - Cell stem cell, 2017 - cell.com
Classical lissencephaly is a genetic neurological disorder associated with mental
retardation and intractable epilepsy, and Miller-Dieker syndrome (MDS) is the most severe …
retardation and intractable epilepsy, and Miller-Dieker syndrome (MDS) is the most severe …
Spatio-temporal transcriptome of the human brain
Brain development and function depend on the precise regulation of gene expression.
However, our understanding of the complexity and dynamics of the transcriptome of the …
However, our understanding of the complexity and dynamics of the transcriptome of the …
Multiple knockout mouse models reveal lincRNAs are required for life and brain development
Many studies are uncovering functional roles for long noncoding RNAs (lncRNAs), yet few
have been tested for in vivo relevance through genetic ablation in animal models. To …
have been tested for in vivo relevance through genetic ablation in animal models. To …