Huperzine A (HupA), an alkaloid found in the club moss Huperzia serrata, has been used for
centuries in Chinese folk medicine to treat dementia. The effects of this alkaloid have been …

Intracerebral hemorrhage (ICH) is a destructive form of stroke that often results in death or
disability. However, the survivors usually experience sequelae of neurological impairments …

Astrocytes release functional mitochondria (Mt) that play regulatory and prosurvival functions
on entering adjacent cells. We recently demonstrated that these released Mts could enter …

Mitochondria are dynamic organelles responsible for cellular energy production. Besides,
regulating energy homeostasis, mitochondria are responsible for calcium homeostasis …

Huperzine A (HupA) is an acetylcholinesterase (AChE) inhibitor extracted from Huperzia
Serrata, a firmoss, which has been used for various diseases in traditional Chinese …

Intracerebral hemorrhage is a life-threatening condition with a high fatality rate and severe
sequelae. However, there is currently no treatment available for intracerebral hemorrhage …

Astrocytes are an integral component of the neurovascular unit where they act as
homeostatic regulators, especially after brain injuries, such as stroke. One process by which …

Mitochondrial oxidative stress has been implicated in various forms of brain injury, both
traumatic and non-traumatic. Due to its oxidative demand, the brain is intimately dependent …

In recent years, complementary and alternative medicine has become popular among the
general population due to their lower side effects, cost-effectiveness, ready availability, and …

Aim: Iron dyshomeostasis is one of the primary causes of neuronal death in Alzheimer's
disease (AD). Huperzine A (HupA), a natural inhibitor of acetylcholinesterase (AChE), is a …