Cytochrome P450s (CYPs) are a large family of heme-containing monooxygenase enzymes
involved in the first-pass metabolism of drugs and foreign chemicals in the body. CYP …

Cytochrome P450s are heme-thiolate enzymes that have been broadly applied in
pharmaceutical and biosynthesis because of their efficient oxidation at inert carbons …

Drug metabolism in human liver is a process involving many different enzymes. Among
them, a number of cytochromes P450 isoforms catalyze the oxidation of most of the drugs …

Improving the electrochemical performance of cytochrome P450 enzymes is highly desirable
due to their versatility in the recognition of different biological and xenobiotic compounds …

This study described the bioelectrochemistry of hemoglobin (Hb) at multiwall carbon
nanotubes (MWCNTs) noncovalently functionalized with biopolymers of sodium alginate …

Heme proteins take part in a number of fundamental biological processes, including oxygen
transport and storage, electron transfer, catalysis and signal transduction. The redox …

In the present work, screen-printed electrodes (SPE) modified with a synthetic surfactant,
didodecyldimethylammonium bromide (DDAB) and streptolysin O (SLO) were prepared for …

Cytochrome (cyt) P450s comprise the enzyme superfamily responsible for human oxidative
metabolism of a majority of drugs and xenobiotics. Electronic delivery of electrons to cyt …

This review covers the current state of knowledge regarding artificial fusion constructs of
cytochrome P 450 enzymes in which the activity of the catalytic heme is driven by reductases …

Polymorphism is an important aspect in drug metabolism responsible for different individual
response to drug dosage, often leading to adverse drug reactions. Here human CYP2C9 as …