Modern subunit vaccines based on homogeneous antigens offer more precise targeting and
improved safety compared with traditional whole-pathogen vaccines. However, they are also …

Natural biopolymers have inspired the development of synthetic analogues that can adopt
defined conformations and assemble into 3D architectures. These compounds are mainly …

The primary sequence of a biopolymer encodes the essential information for folding,
permitting to carry out sophisticated functions. Inspired by natural biopolymers, peptide and …

Glycans are involved in various life processes and represent critical targets of biomedical
developments. Nevertheless, the accessibility to long glycans with precise structures …

Highlights•NMR methods are of paramount importance to deduce structure, dynamics and
recognition of complex glycans.•The intrinsic low sensitivity of NMR for studying glycans and …

This perspective article is focused on the presentation of the latest advances in NMR
methods and applications that are behind the exciting achievements in the understanding of …

Pseudomonas aeruginosa belongs to the group of three “critical priority” multi-drug-resistant
pathogens listed by WHO and is responsible for severe and often deadly infections such as …

Herein, we described the first synthesis of the pentasaccharide and decasaccharide of the A.
baumannii ATCC 17961 O‐antigen for developing a synthetic carbohydrate‐based vaccine …

The stereoselectivity of glycosidic bond formation continues to pose a noteworthy hurdle in
synthesizing carbohydrates, primarily due to the simultaneous occurrence of SN1 and SN2 …

Glycosylation is a common post-translational modification that occurs during the production
of antibodies. Glycans attached to antibodies play an important role in the pharmacokinetics …