Vitamin D shows a variety of pleiotropic activities which cannot be fully explained by the
stimulation of classic pathway-and vitamin D receptor (VDR)-dependent transcriptional …

Melanoma, a tumor arising from a melanocyte (the cell responsible for producing pigment),
continues to carry the potential to be a deadly disease. In the United States, 91,320 new …

A role for vitamin D in immune modulation and in cancer has been suggested. In this work,
we report that mice with increased availability of vitamin D display greater immune …

Background: Vitamin D exerts multiple beneficial effects in humans, including neuronal,
immune, and bone homeostasis and the regulation of cardiovascular functions. Recent …

Melanoma is a deadly skin cancer that becomes especially difficult to treat after it
metastasizes. Timely identification of melanoma is critical for effective therapy, but …

Ultraviolet (UV) light is absorbed by nucleic acids, proteins or other endogenous
chromophores, such as porphyrins, flavins and melanin, triggering biological processes in …

Melanoma is one of the most lethal types of skin cancer, with a poor prognosis once the
disease enters metastasis. The efficacy of currently available treatment schemes for …

Dietary supplements are commonly recommended by dermatologists in the treatment of
skin, hair, and nail disorders. This review of oral over-the-counter supplement use in …

Patients with newly resected stage II melanoma (n= 104) were randomized to receive
adjuvant vitamin D3 (100,000 IU every 50 days) or placebo for 3 years to investigate vitamin …

Melanoma is considered a lethal and treatment-resistant skin cancer with a high risk of
recurrence, making it a major clinical challenge. Our earlier studies documented that 1, 25 …