Focusing on the recent literature (since 2000), this review outlines the main synthetic
approaches for the preparation of 5′-mono-, 5′-di-, and 5′-triphosphorylated …

Sugar-nucleoside diphosphates (sugar-nucleotides) are imperative to carbohydrate
metabolism and glycoconjugate biosynthesis. They are composed of an activated sugar …

We described the integration of the general reversibility of glycosyltransferase-catalyzed
reactions, artificial glycosyl donors, and a high throughput colorimetric screen to enable the …

Sulfur (VI) fluoride motifs are important entities in organic chemistry. Typically, their
syntheses involve the corresponding chlorides, which are often difficult to prepare and …

Along with a growing interest in mRNA-based gene therapies, efforts are increasingly
focused on reaching the full translational potential of mRNA, as a major obstacle for in vivo …

P‐Amidites can be used in iterative couplings to selectively give mixed PIII–PV anhydrides.
These intermediates can be oxidized followed by a rapid removal of the two terminal …

Oligophosphates play essential roles in biochemistry, and considerable research has been
directed toward the synthesis of both naturally occurring oligophosphates and their synthetic …

Methylcytosine and methylated histones have been considered for a long time as stable
epigenetic marks of chromatin involved in gene regulation. This concept has been recently …

We describe a general method for the elongation of nucleoside oligophosphate chains by
means of cyanoethyl (CE) phosphorimidazolides. Though the method requires a …

Esters and anhydrides of phosphoric acid are essential in biology. It is very difficult to identify
processes in life that do not involve these modifications and their transformation at some …