The neuroconnectionist research programme

A Doerig, RP Sommers, K Seeliger… - Nature Reviews …, 2023 - nature.com
Artificial neural networks (ANNs) inspired by biology are beginning to be widely used to
model behavioural and neural data, an approach we call 'neuroconnectionism'. ANNs have …

The prefrontal cortex, pathological anxiety, and anxiety disorders

MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

A metaverse: Taxonomy, components, applications, and open challenges

SM Park, YG Kim - IEEE access, 2022 - ieeexplore.ieee.org
Unlike previous studies on the Metaverse based on Second Life, the current Metaverse is
based on the social value of Generation Z that online and offline selves are not different …

Medial and orbital frontal cortex in decision-making and flexible behavior

MC Klein-Flügge, A Bongioanni, MFS Rushworth - Neuron, 2022 - cell.com
The medial frontal cortex and adjacent orbitofrontal cortex have been the focus of
investigations of decision-making, behavioral flexibility, and social behavior. We review …

Unique functional responses differentially map onto genetic subtypes of dopamine neurons

M Azcorra, Z Gaertner, C Davidson, Q He, H Kim… - Nature …, 2023 - nature.com
Dopamine neurons are characterized by their response to unexpected rewards, but they
also fire during movement and aversive stimuli. Dopamine neuron diversity has been …

Computational models link cellular mechanisms of neuromodulation to large-scale neural dynamics

JM Shine, EJ Müller, B Munn, J Cabral, RJ Moran… - Nature …, 2021 - nature.com
Decades of neurobiological research have disclosed the diverse manners in which the
response properties of neurons are dynamically modulated to support adaptive cognitive …

Deep reinforcement learning and its neuroscientific implications

M Botvinick, JX Wang, W Dabney, KJ Miller… - Neuron, 2020 - cell.com
The emergence of powerful artificial intelligence (AI) is defining new research directions in
neuroscience. To date, this research has focused largely on deep neural networks trained …

Dopamine transients follow a striatal gradient of reward time horizons

A Mohebi, W Wei, L Pelattini, K Kim, JD Berke - Nature Neuroscience, 2024 - nature.com
Animals make predictions to guide their behavior and update those predictions through
experience. Transient increases in dopamine (DA) are thought to be critical signals for …

Wave-like dopamine dynamics as a mechanism for spatiotemporal credit assignment

AA Hamid, MJ Frank, CI Moore - Cell, 2021 - cell.com
Significant evidence supports the view that dopamine shapes learning by encoding reward
prediction errors. However, it is unknown whether striatal targets receive tailored dopamine …

Navigating for reward

M Sosa, LM Giocomo - Nature Reviews Neuroscience, 2021 - nature.com
An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …