Aptamer‐based extracellular vesicle isolation, analysis and therapeutics

L Zhu, W Tian, L Yuan, C Chi, Y Wang… - Interdisciplinary …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) play an important role in many physiological processes. Thus,
EV analysis has a great value for the understanding of mechanisms underlying disease …

Radiolabelling small and biomolecules for tracking and monitoring

MR Edelmann - RSC advances, 2022 - pubs.rsc.org
Radiolabelling small molecules with beta-emitters has been intensively explored in the last
decades and novel concepts for the introduction of radionuclides continue to be reported …

Screening and multiple detection of cancer exosomes using an SERS-based method

Z Wang, S Zong, Y Wang, N Li, L Li, J Lu, Z Wang… - Nanoscale, 2018 - pubs.rsc.org
As a kind of most important cancer biomarker, exosomes are getting more frequently
investigated in cancer diagnosis. In this study, we proposed an SERS-based method for the …

Application of aptamers in diagnostics, drug-delivery and imaging

C Chandola, S Kalme, MG Casteleijn, A Urtti… - Journal of …, 2016 - Springer
Aptamers are small, single-stranded oligonucleotides (DNA or RNA) that bind to their target
with high specificity and affinity. Although aptamers are analogous to antibodies for a wide …

Aptamer-based technology for radionuclide targeted imaging and therapy: A promising weapon against cancer

L Filippi, O Bagni, C Nervi - Expert Review of Medical Devices, 2020 - Taylor & Francis
Introduction aptamers are short artificial, single-strand oligonucleotide sequences (DNA,
RNA or modified RNA), capable of binding to biological molecules with high affinity and …

Pure DNA scaffolded drug delivery systems for cancer therapy

H Aliouat, Y Peng, Z Waseem, S Wang, W Zhou - Biomaterials, 2022 - Elsevier
The development of effective drug delivery system is highly important for targeted tumor
therapy. Over the past few decades, a number of biomaterials have been extensively …

Radiolabeling of functional oligonucleotides for molecular imaging

D Liu, Q Xia, D Ding, W Tan - Frontiers in Bioengineering and …, 2022 - frontiersin.org
Molecular imaging has greatly advanced basic biology and translational medicine through
visualization and quantification of molecular events in a cellular context and living …

RNA nanostructures for targeted drug delivery and imaging

L Teodori, M Omer, J Kjems - RNA biology, 2024 - Taylor & Francis
The RNA molecule plays a pivotal role in many biological processes by relaying genetic
information, regulating gene expression, and serving as molecular machines and catalyzers …

Nucleic acid-based treatments against COVID-19: potential efficacy of aptamers and siRNAs

J Khanali, M Azangou-Khyavy, Y Asaadi… - Frontiers in …, 2021 - frontiersin.org
Despite significant efforts, there are currently no approved treatments for COVID-19.
However, biotechnological approaches appear to be promising in the treatment of the …

Aptamers as radiopharmaceuticals for nuclear imaging and therapy

M Gijs, A Aerts, N Impens, S Baatout, A Luxen - Nuclear medicine and …, 2016 - Elsevier
Today, radiopharmaceuticals belong to the standard instrumentation of nuclear medicine,
both in the context of diagnosis and therapy. The majority of radiopharmaceuticals consist of …