Single cell RNA sequencing: A new frontier in pancreatic ductal adenocarcinoma

M Bou Zerdan, M Shatila, D Sarwal, Y Bouferraa… - Cancers, 2022 - mdpi.com
Simple Summary Pancreatic cancer has a very low survival rate for several reasons. One of
those is primarily due to the difficulty in diagnosing it at an early stage. For this reason, it is …

[PDF][PDF] Modeling Susceptibility to Cardiotoxicity in Cancer Therapy Using Human iPSC-Derived Cardiac Cells and Systems Biology

MK Mullen, WLW Tan, JW Rhee, JC Wu - Heart Failure Clinics, 2022 - Elsevier
The development of human-induced pluripotent stem cell (iPSC)-derived cardiac cell types
has created a new paradigm in assessing drug-induced cardiotoxicity. Advances in …

[HTML][HTML] SMOX expression predicts the prognosis of non-small cell lung cancer

Z Huang, S Wang, HJ Zhang, YL Zhou… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background The development of non-small cell lung cancer (NSCLC) is very rapid, and the
effect of its treatment is often closely related to the diagnosis time of the disease. Therefore …

A signature based on chromatin regulation and tumor microenvironment infiltration in clear cell renal cell carcinoma

C Yang, T Yu, Q Lin - Epigenomics, 2022 - Taylor & Francis
Aims: This research aimed to construct a signature based on chromatin regulation in
localized clear cell renal cell carcinoma (ccRCC). Materials & methods: Non-negative matrix …

Current and emerging technologies for the analysis of the genome-wide and locus-specific DNA methylation patterns

J Tost - DNA Methyltransferases-Role and Function, 2022 - Springer
DNA methylation is the most studied epigenetic modification, and altered DNA methylation
patterns have been identified in cancer and more recently also in many other complex …