Legacy and emerging per-and polyfluoroalkyl substances: analytical techniques, environmental fate, and health effects

RA Brase, EJ Mullin, DC Spink - International journal of molecular …, 2021 - mdpi.com
Due to their unique chemical properties, per-and polyfluoroalkyl substances (PFAS) have
been used extensively as industrial surfactants and processing aids. While several types of …

PFAS environmental pollution and antioxidant responses: an overview of the impact on human field

M Bonato, F Corrà, M Bellio, L Guidolin… - International journal of …, 2020 - mdpi.com
Due to their unique properties, perfluorinated substances (PFAS) are widely used in multiple
industrial and commercial applications, but they are toxic for animals, humans included. This …

Perfluoroalkyl substances (PFAS) adsorption in drinking water by granular activated carbon: Influence of activated carbon and PFAS characteristics

B Cantoni, A Turolla, J Wellmitz, AS Ruhl… - Science of The Total …, 2021 - Elsevier
Perfluoroalkyl substances (PFAS) persistence in the environment leads to their presence in
drinking water, that is of high concern due to their potential human health risk. Adsorption …

The toxicology of perfluorooctanoate

GL Kennedy, JL Butenhoff, GW Olsen… - Critical reviews in …, 2004 - Taylor & Francis
ABSTRACT PFOA is a peroxisome proliferator (PPAR agonist) and exerts morphological
and biochemical effects characteristic of PPAR agonists. These effects include increased β …

Molecular mechanisms of PFOA-induced toxicity in animals and humans: Implications for health risks

K Li, P Gao, P Xiang, X Zhang, X Cui, LQ Ma - Environment international, 2017 - Elsevier
As an emerging persistent organic pollutant (POP), perfluorooctanoate (PFOA) is one of the
most abundant perfluorinated compounds (PFCs) in the environment. This review …

Application of the key characteristics of carcinogens to per and polyfluoroalkyl substances

AM Temkin, BA Hocevar, DQ Andrews… - International journal of …, 2020 - mdpi.com
Per-and polyfluoroalkyl substances (PFAS) constitute a large class of environmentally
persistent chemicals used in industrial and consumer products. Human exposure to PFAS is …

Evaluation of the individual and combined toxicity of perfluoroalkyl substances to human liver cells using biomarkers of oxidative stress

AF Ojo, Q Xia, C Peng, JC Ng - Chemosphere, 2021 - Elsevier
Although human exposure is to mixtures of per-and polyfluoroalkyl substances (PFAS), their
combined effects and underlying mechanisms remain largely unknown. In this study, the …

Perfluoroalkylated substances (PFAS) affect oxidative stress biomarkers in vitro

M Wielsøe, M Long, M Ghisari, EC Bonefeld-Jørgensen - Chemosphere, 2015 - Elsevier
Perfluoroalkylated substances (PFAS) have been widely used since 1950s and humans are
exposed through food, drinking water, consumer products, dust, etc. The long-chained PFAS …

Toward a mechanistic understanding of poly-and perfluoroalkylated substances and cancer

RI Boyd, S Ahmad, R Singh, Z Fazal, GS Prins… - Cancers, 2022 - mdpi.com
Simple Summary Poly-and perfluoroalkylated substances (PFAS) are industrial chemicals
found in many household products that persist in the environment. While several excellent …

Studies on the toxicological effects of PFOA and PFOS on rats using histological observation and chemical analysis

L Cui, Q Zhou, C Liao, J Fu, G Jiang - Archives of environmental …, 2009 - Springer
As an emerging class of environmentally persistent and bioaccumulative contaminants,
perfluorinated compounds (PFCs), especially perfluorooctanoic acid (PFOA) and …