Promoting the suitability of graphitic bio-carbon nitride and metal oxide nanoparticles: A review of sulfonamides photocatalytic degradation
The widespread consumption of pharmaceutical drugs and their incomplete breakdown in
organisms has led to their extensive presence in aquatic environments. The indiscriminate …
organisms has led to their extensive presence in aquatic environments. The indiscriminate …
Lower rim thiacalixarenes derivatives incorporating multiple coordinating carbonyl groups: Synthesis, characterization, ion-responsive ability and DFT computational …
A Abdou, OA Omran, JH Al-Fahemi, RS Jassas… - Journal of Molecular …, 2023 - Elsevier
Three novel tetra substituted p‑tert-butylthiacalix [4] arene derivatives (3, 4, and 5) with five
coordinating carbonyl groups at the lower rims were synthesized. Accordingly, diethyl tetra-t …
coordinating carbonyl groups at the lower rims were synthesized. Accordingly, diethyl tetra-t …
Thiazole-pyrazoline hybrids as potential antimicrobial agent: Synthesis, biological evaluation, molecular docking, DFT studies and POM analysis
In this study, an efficient synthesis of new thiazole-pyrazoline hybrids was investigated and
hybrids were screened for their antimicrobial activities against four species of pathogenic …
hybrids were screened for their antimicrobial activities against four species of pathogenic …
In vitro and in vivo evaluation of the antimicrobial, antioxidant, cytotoxic, hemolytic activities and in silico POM/DFT/DNA-binding and pharmacokinetic analyses of …
SA Hassan, DM Aziz, MN Abdullah… - Journal of …, 2024 - Taylor & Francis
In this work, Schiff bases and Thiazolidin-4-ones, were synthesized using Sonication and
Microwave techniques, respectively. The Schiff base derivatives (3a–b) were synthesized …
Microwave techniques, respectively. The Schiff base derivatives (3a–b) were synthesized …
Crystal structure, Hirshfeld surface and DFT computations, along with molecular docking investigations of a new pyrazole as a tyrosine kinase inhibitor
M Chalkha, AA el Hassani, A Nakkabi, B Tüzün… - Journal of Molecular …, 2023 - Elsevier
In the present work we report the experimental and computational investigations of (2-
aminophenyl)[4-(4-chlorophenyl)-1, 3-diphenyl-1H-pyrazol-5-yl] methanone (C 28 H 20 ClN …
aminophenyl)[4-(4-chlorophenyl)-1, 3-diphenyl-1H-pyrazol-5-yl] methanone (C 28 H 20 ClN …
Design, synthesis, in-vitro and in-silico studies of chromone‐isoxazoline conjugates as anti‐bacterial agents
Y Kanzouai, M Chalkha, H Hadni, M Laghmari… - Journal of Molecular …, 2023 - Elsevier
A novel series of chromone-isoxazoline conjugates was successfully synthesized by the O-
alkylation and 1, 3-dipolar cycloaddition reactions using methyl 7‑hydroxy-4H-chromone-3 …
alkylation and 1, 3-dipolar cycloaddition reactions using methyl 7‑hydroxy-4H-chromone-3 …
Recent Progress in Synthesis of Sulfonamides and N‐Acylsulfonamides, Biological Applications and Their Structure‐Activity Relationship (SAR) Studies
In recent years, sulfonamide and N‐acylsulfonamide have emerged as prominent areas of
scientific research across multiple fields, including chemistry, biology, and medicine. The …
scientific research across multiple fields, including chemistry, biology, and medicine. The …
Synthesis, characterization, DFT mechanistic study, antimicrobial activity, molecular modeling, and ADMET properties of novel pyrazole-isoxazoline hybrids
M Chalkha, H Nour, K Chebbac, A Nakkabi… - ACS …, 2022 - ACS Publications
A series of new heterocycle hybrids incorporating pyrazole and isoxazoline rings was
successfully synthesized, characterized, and evaluated for their antimicrobial responses …
successfully synthesized, characterized, and evaluated for their antimicrobial responses …
[HTML][HTML] In vitro and in silico evaluation of the antimicrobial and antioxidant activities of spiropyrazoline oxindole congeners
M Chalkha, K Chebbac, H Nour, A Nakkabi… - Arabian Journal of …, 2024 - Elsevier
The search for novel powerful antimicrobial and antioxidant agents is considered a dynamic
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
field in medicinal chemistry. In this context, a series of spiropyrazoline indolin-3-one …
Design, synthesis, In-vitro, In-silico and DFT studies of novel functionalized isoxazoles as antibacterial and antioxidant agents
A Arzine, O Abchir, M Chalkha, K Chebbac… - … Biology and Chemistry, 2024 - Elsevier
A series of new isoxazolederivatives incorporating the sulfonate ester function has been
synthesized from 2-benzylidenebenzofuran-3 (2 H)-one, known as aurone. The synthesis of …
synthesized from 2-benzylidenebenzofuran-3 (2 H)-one, known as aurone. The synthesis of …