Intravenous fat emulsion: a potential novel antidote

DE Turner-Lawrence, W Kerns - Journal of medical toxicology, 2008 - Springer
Intravenous fat emulsions (IFE) are traditionally used as a component of parenteral nutrition
therapy. Recently, IFE was used to resuscitate severe local anesthetic drug toxicity. This …

Injectable nanocarriers for biodetoxification

JC Leroux - Nature Nanotechnology, 2007 - nature.com
Hospitals routinely treat patients suffering from overdoses of drugs or other toxic chemicals
as a result of illicit drug consumption, suicide attempts or accidental exposures. However, for …

[图书][B] The handbook of nanomedicine

KK Jain, KK Jain - 2008 - Springer
Nanomedicine is defined as the application of nanobiotechnology to medicine. It is a
discipline at the interface of medicine and nanobiotechnology but is not a subspecialty of …

The effects of lipid infusion on myocardial function and bioenergetics in l-bupivacaine toxicity in the isolated rat heart

SN Stehr, JC Ziegeler, A Pexa, R Oertel… - Anesthesia & …, 2007 - journals.lww.com
BACKGROUND: It is unclear whether improved metabolism or a “lipid sink” effect of lipid
infusion is responsible for the positive effects in local anesthetic-induced myocardial …

Physicochemical properties and blood compatibility of acylated chitosan nanoparticles

DW Lee, K Powers, R Baney - Carbohydrate polymers, 2004 - Elsevier
Chitosan was N-acylated with butanoic, hexanoic and benzoic anhydride under
homogeneous conditions in the presence of methanol. The degree of substitution of N-acyl …

[图书][B] Surfactant science and technology: retrospects and prospects

LS Romsted - 2014 - books.google.com
Surfactant research explores the forces responsible for surfactant assembly and the critical
industrial, medical, and personal applications, including viscosity control, microelectronics …

Transmembrane pH-gradient liposomes to treat cardiovascular drug intoxication

N Bertrand, C Bouvet, P Moreau, JC Leroux - ACS nano, 2010 - ACS Publications
Injectable scavenging nanocarriers have been proposed as detoxifying agents when there
are no specific antidotes to treat pharmacological overdoses. They act by capturing the drug …

Photo-responsive polymer nanocapsules

V Marturano, P Cerruti, C Carfagna, M Giamberini… - Polymer, 2015 - Elsevier
This work reports on the preparation of UV-light responsive nanocapsules based on cross-
linked polyamide, obtained by miniemulsion interfacial polymerization. The photo-triggered …

Enhanced antioxidant bioactivity of Salvia miltiorrhiza (Danshen) products prepared using nanotechnology

JR Liu, GF Chen, HN Shih, PC Kuo - Phytomedicine, 2008 - Elsevier
The traditional Chinese medicine, Salvia miltiorrhiza (Danshen), promotes blood circulation
and relieves blood stasis, also demonstrating good antioxidant activity. In the present study …

From micro-to nanostructured implantable device for local anesthetic delivery

L Zorzetto, P Brambilla, E Marcello… - International Journal …, 2016 - Taylor & Francis
Local anesthetics block the transmission of painful stimuli to the brain by acting on ion
channels of nociceptor fibers, and find application in the management of acute and chronic …