Current clinical landscape and global potential of bacteriophage therapy

NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

Current therapies and challenges for the treatment of Staphylococcus aureus biofilm‐related infections

NN Tran, T Morrisette, SCJ Jorgensen… - … : The Journal of …, 2023 - Wiley Online Library
Staphylococcus aureus is a major cause of nosocomial and community‐acquired infections
and contributes to significant increase in morbidity and mortality especially when associated …

Optimization of phage-antibiotic combinations against Staphylococcus aureus biofilms

R Kebriaei, SM Lehman, RM Shah… - Microbiology …, 2023 - Am Soc Microbiol
Phage therapy has gained attention due to the spread of antibiotic-resistant bacteria and
narrow pipeline of novel antibiotics. Phage cocktails are hypothesized to slow the overall …

The combination of antibiotic and non-antibiotic compounds improves antibiotic efficacy against multidrug-resistant bacteria

G Xiao, J Li, Z Sun - International Journal of Molecular Sciences, 2023 - mdpi.com
Bacterial antibiotic resistance, especially the emergence of multidrug-resistant (MDR)
strains, urgently requires the development of effective treatment strategies. It is always of …

Phage-antibiotic combinations against multidrug-resistant Pseudomonas aeruginosa in in vitro static and dynamic biofilm models

DJ Holger, A El Ghali, N Bhutani, KL Lev… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Biofilm-producing Pseudomonas aeruginosa infections pose a severe threat to public health
and are responsible for high morbidity and mortality. Phage-antibiotic combinations (PACs) …

Phage-antibiotic combinations to control Pseudomonas aeruginosaCandida two-species biofilms

P Manohar, B Loh, R Nachimuthu, S Leptihn - Scientific Reports, 2024 - nature.com
Phage-antibiotic combinations to treat bacterial infections are gaining increased attention
due to the synergistic effects often observed when applying both components together. Most …

Synergistic bactericidal effects of phage-enhanced antibiotic therapy against MRSA biofilms

AJ Kunz Coyne, K Stamper, C Bleick… - Microbiology …, 2024 - Am Soc Microbiol
Methicillin-resistant Staphylococcus aureus (MRSA) causes biofilm-related medical device
infections. Phage-antibiotic combinations offer potential therapy due to proven in vitro …

Synergistic Effects of Bacteriophage vB_Eco4-M7 and Selected Antibiotics on the Biofilm Formed by Shiga Toxin-Producing Escherichia coli

A Necel, S Bloch, G Topka-Bielecka, A Janiszewska… - Antibiotics, 2022 - mdpi.com
Apart from antibiotic resistance of pathogenic bacteria, the formation of biofilms is a feature
that makes bacterial infections especially difficulty to treat. Shiga toxin-producing …

Bacteriophage therapy for drug-resistant Staphylococcus aureus infections

K Liu, C Wang, X Zhou, X Guo, Y Yang… - Frontiers in Cellular …, 2024 - frontiersin.org
Drug-resistant Staphylococcus aureus stands as a prominent pathogen in nosocomial and
community-acquired infections, capable of inciting various infections at different sites in …

Pathophysiology and management of Staphylococcus aureus in nasal polyp disease

Z Xu, J Yan, W Wen, N Zhang… - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Staphylococcus aureus (S. aureus) is a common pathogen that frequently
colonizes the sinonasal cavity. Recent studies demonstrated the essential role of …