Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED)

JA Platts-Mills, S Babji, L Bodhidatta, J Gratz… - The Lancet Global …, 2015 - thelancet.com
Background Most studies of the causes of diarrhoea in low-income and middle-income
countries have looked at severe disease in people presenting for care, and there are few …

Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

LV Blanton, MR Charbonneau, T Salih, MJ Barratt… - Science, 2016 - science.org
INTRODUCTION As we come to appreciate how our microbial communities (microbiota)
assemble following birth, there is an opportunity to determine how this facet of our …

The MAL-ED study: a multinational and multidisciplinary approach to understand the relationship between enteric pathogens, malnutrition, gut physiology, physical …

Clinical Infectious Diseases, 2014 - academic.oup.com
Highly prevalent conditions with multiple and complex underlying etiologies are a challenge
to public health. Undernutrition, for example, affects 20% of children in the developing world …

Epidemiology and Impact of Campylobacter Infection in Children in 8 Low-Resource Settings: Results From the MAL-ED Study

C Amour, J Gratz, E Mduma, E Svensen… - Clinical Infectious …, 2016 - academic.oup.com
Background. Enteropathogen infections have been associated with enteric dysfunction and
impaired growth in children in low-resource settings. In a multisite birth cohort study (MAL …

Cultivating healthy growth and nutrition through the gut microbiota

S Subramanian, LV Blanton, SA Frese… - Cell, 2015 - cell.com
Microbiota assembly is perturbed in children with undernutrition, resulting in persistent
microbiota immaturity that is not rescued by current nutritional interventions. Evidence is …

Practical application of linear growth measurements in clinical research in low-and middle-income countries

JM Wit, JH Himes, S Van Buuren, DM Denno… - Hormone research in …, 2017 - karger.com
Abstract Background/Aims: Childhood stunting is a prevalent problem in low-and middle-
income countries and is associated with long-term adverse neurodevelopment and health …

[HTML][HTML] Fecal markers of environmental enteropathy and subsequent growth in Bangladeshi children

MB Arndt, BA Richardson, T Ahmed… - The American journal …, 2016 - ncbi.nlm.nih.gov
Environmental enteropathy (EE), a subclinical intestinal disorder characterized by mucosal
inflammation, reduced barrier integrity, and malabsorption, appears to be associated with …

[HTML][HTML] Dynamics and trends in fecal biomarkers of gut function in children from 1–24 months in the MAL-ED study

BJJ McCormick, GO Lee, JC Seidman… - The American journal …, 2017 - ncbi.nlm.nih.gov
Growth and development shortfalls that are disproportionately prevalent in children living in
poor environmental conditions are postulated to result, at least in part, from abnormal gut …

Aflatoxin exposure during the first 36 months of life was not associated with impaired growth in Nepalese children: an extension of the MAL-ED study

NJ Mitchell, HH Hsu, RK Chandyo, B Shrestha… - PloS one, 2017 - journals.plos.org
Exposure to aflatoxin, a mycotoxin common in many foods, has been associated with child
growth impairment in sub-Saharan Africa. To improve our understanding of growth …

Interactions between fecal gut microbiome, enteric pathogens, and energy regulating hormones among acutely malnourished rural Gambian children

HM Nabwera, JL Espinoza, A Worwui, M Betts… - …, 2021 - thelancet.com
Background The specific roles that gut microbiota, known pathogens, and host energy-
regulating hormones play in the pathogenesis of non-edematous severe acute malnutrition …