Cancer is the second major cause of disease-related death worldwide, and its accurate
early diagnosis and therapeutic intervention are fundamental for saving the patient's life …

Tumors are complex tissues of cancerous cells surrounded by a heterogeneous cellular
microenvironment with which they interact. Single-cell sequencing enables molecular …

Cell atlases are essential companions to the genome as they elucidate how genes are used
in a cell type–specific manner or how the usage of genes changes over the lifetime of an …

Single cell profiling has been proven to be a powerful tool in molecular biology to
understand the complex behaviours of heterogeneous system. The definition of the …

The identification and characterization of circulating tumor cells (CTCs) are important for
gaining insights into the biology of metastatic cancers, monitoring disease progression, and …

Single cell RNA sequencing (scRNA-seq) allows global transcriptomic profiling at a cellular
resolution, thus, identifying underlying cell types and corresponding lineages. Such cell type …

Background Single-cell transcriptome sequencing (scRNA-Seq) has allowed new types of
investigations at unprecedented levels of resolution. Among the primary goals of scRNA …

The recent advances in single-cell RNA sequencing (scRNA-seq) techniques have
stimulated efforts to identify and characterize the cellular composition of complex tissues …

Many single cell RNA-sequencing (scRNA-seq) data analysis workflows rely on methods
that embed and visualize the properties of a k-nearest neighbor (kNN) graph in two …

Aged traumatic brain injury (TBI) patients suffer increased mortality and long-term
neurocognitive and neuropsychiatric morbidity compared with younger patients. Microglia …